Meegdes B H, Ingenhoes R, Peeters L L, Exalto N
Department of Obstetrics and Gynecology, R.K. Ziekenhuis Mariastichting, Central Laboratory of Pathology and Cytology, G.G.D., Haarlem, The Netherlands.
Fertil Steril. 1988 Feb;49(2):216-20. doi: 10.1016/s0015-0282(16)59704-0.
The chorionic villous vascularization of 40 patients with first trimester spontaneous abortion was compared with that of 10 patients undergoing legal abortion (control group). The spontaneous abortion group was subdivided into a group with intrauterine embryonic death (n = 20) and a group with blighted ova (n = 20). Villous vascularization appeared unaffected after prolonged postmortem intrauterine retention. The incidence of vascularized villi was 89% in the control group, 26% in the group with embryonic death, and 9% in the group with blighted ova. In addition, the vascular density of vascularized villi was three to four times higher in the control group than in the two spontaneous abortion groups. The present study provides evidence that, in case of embryonic death and blighted ova, chorionic villous vascularization is deficient.
将40例孕早期自然流产患者的绒毛膜绒毛血管形成情况与10例接受合法堕胎的患者（对照组）进行比较。自然流产组又分为宫内胚胎死亡组（n = 20）和枯萎卵组（n = 20）。长时间死后宫内滞留后，绒毛血管形成似乎未受影响。对照组血管化绒毛的发生率为89%，胚胎死亡组为26%，枯萎卵组为9%。此外，对照组血管化绒毛的血管密度比两个自然流产组高3至4倍。本研究提供了证据，表明在胚胎死亡和枯萎卵的情况下，绒毛膜绒毛血管形成不足。
