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Identification of two species of suppressive factor of differing molecular weight released by in vitro fertilized human oocytes.

作者信息

Daya S, Clark D A

机构信息

Department of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.

出版信息

Fertil Steril. 1988 Feb;49(2):360-3. doi: 10.1016/s0015-0282(16)59729-5.

DOI:10.1016/s0015-0282(16)59729-5
PMID:3338591
Abstract

Preimplantation human embryos have been shown to release factors that have immunosuppressive activity and that are highly correlated with successful implantation. The present study was undertaken to determine the molecular weight of these factors using HPLC. Two peaks of suppressive activity were found associated with molecular weights of 3.7 +/- 0.3 and 1.2 +/- 0.1 kd, respectively. The potential significance of low molecular weight immunosuppressor factors in avoiding maternal inflammatory and immunologic responses is discussed.

摘要

相似文献

1
Identification of two species of suppressive factor of differing molecular weight released by in vitro fertilized human oocytes.
Fertil Steril. 1988 Feb;49(2):360-3. doi: 10.1016/s0015-0282(16)59729-5.
2
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引用本文的文献

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Systematic Review of Postfertilization Effects and Potential for Embryo Formation and Loss during the Use of Intrauterine Devices.宫内节育器使用期间受精后效应及胚胎形成与丢失可能性的系统评价
Linacre Q. 2020 Feb;87(1):60-77. doi: 10.1177/0024363919854289. Epub 2019 Jun 27.
2
An update on the identity of early pregnancy factor and its role in early pregnancy.早期妊娠因子的身份及其在早期妊娠中的作用的最新进展。
J Assist Reprod Genet. 1997 Oct;14(9):497-9. doi: 10.1023/a:1021167024413.
3
The production of interleukin-1 alpha immunoreactivity by human oviductal cells in a coculture system.
人输卵管细胞在共培养系统中白细胞介素-1α免疫反应性的产生。
J Assist Reprod Genet. 1996 Nov;13(10):772-5. doi: 10.1007/BF02066496.
4
High levels of spermine in IVF medium as a negative predictor of subsequent success of embryo transfer.体外受精培养基中高水平的精胺是胚胎移植后续成功的负面预测指标。
J Assist Reprod Genet. 1996 Jul;13(6):464-7. doi: 10.1007/BF02066525.
5
Immunosuppressive activity in human in vitro fertilization (IVF) culture supernatants and prediction of the outcome of embryo transfer: a multicenter trial.
J In Vitro Fert Embryo Transf. 1989 Feb;6(1):51-8. doi: 10.1007/BF01134582.
6
Immunosuppressive activity in human embryo growth media is associated with successful pregnancy: effect of gonadotropin releasing hormone agonist (GnRHa) treatment of patients undergoing in vitro fertilization and embryo transfer (IVF-ET).人胚胎生长培养基中的免疫抑制活性与妊娠成功相关：促性腺激素释放激素激动剂（GnRHa）对接受体外受精和胚胎移植（IVF-ET）患者的治疗效果。
J Clin Immunol. 1990 May;10(3):175-81. doi: 10.1007/BF00917918.