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药房在艾滋病病毒预防及护理连续过程中的作用:一项系统评价

The Role of Pharmacies in the HIV Prevention and Care Continuums: A Systematic Review.

作者信息

Crawford Natalie D, Myers Sky, Young Henry, Klepser Donald, Tung Elyse

机构信息

Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Ann Arbor, MI, USA.

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.

出版信息

AIDS Behav. 2021 Jun;25(6):1819-1828. doi: 10.1007/s10461-020-03111-w. Epub 2021 Jan 2.

Abstract

The role of pharmacists in the treatment of HIV has expanded beyond medication dispensing to include a host of cost-effective, evidence-based strategies across the HIV prevention and care continuums. However, wide-scale adoption of pharmacy-based HIV prevention and treatment interventions has been slow. We conducted a systematic review to evaluate the evidence on the role of pharmacists across the HIV prevention and care continuums. Thirty-two studies were identified, most of which provided evidence of feasibility of HIV testing and efficacy of non-prescription syringe sale services in pharmacies. However, only two studies implemented an experimental design to rigorously test pharmacy-based strategies. Notably, no pharmacy-based strategies have specifically targeted the highest HIV risk populations such as black and Latinx men who have sex with men, women, or trans populations. Efficacy trials and effectiveness studies should rigorously test existing pharmacy-based strategies to build greater support for wide-scale adoption and implementation. Moreover, in order to integrate pharmacies into the strategy to end the HIV epidemic, studies are needed to ensure that pharmacy-based HIV prevention and treatment services can reach the highest risk populations.

摘要

药剂师在艾滋病治疗中的作用已从单纯配药扩展到在艾滋病预防和护理连续过程中采用一系列具有成本效益且基于证据的策略。然而,基于药房的艾滋病预防和治疗干预措施的广泛采用一直很缓慢。我们进行了一项系统综述,以评估药剂师在艾滋病预防和护理连续过程中作用的相关证据。共识别出32项研究,其中大多数提供了艾滋病检测可行性及药房非处方注射器销售服务有效性的证据。然而,只有两项研究采用了实验设计来严格测试基于药房的策略。值得注意的是,没有基于药房的策略专门针对艾滋病风险最高的人群,如与男性、女性或跨性别者发生性行为的黑人及拉丁裔男性。疗效试验和效果研究应严格测试现有的基于药房的策略,以获得更广泛支持从而实现大规模采用和实施。此外,为了将药房纳入终结艾滋病流行的策略中,需要开展研究以确保基于药房的艾滋病预防和治疗服务能够覆盖风险最高的人群。

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