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儿科介入肿瘤学中的血管内治疗方法。

Endovascular approaches in pediatric interventional oncology.

作者信息

Shaikh Raja, Munoz Fernando Gomez

机构信息

Department of Radiology, Boston Children's Hospital and Harvard Medical School, 300 Longwood, Boston, MA-02115, USA.

Hospital Clinic-Hospital Sant Joan de Deu, C/ Villarroel 170, Passeig de Sant Joan de Déu, 2, Esplugues del Llobregat, 08950, Barcelona, Spain.

出版信息

CVIR Endovasc. 2021 Jan 2;4(1):2. doi: 10.1186/s42155-020-00190-7.

DOI:10.1186/s42155-020-00190-7
PMID:33387076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7778666/
Abstract

The demand for interventional oncological (IO) treatment of pediatric cancers is becoming increasingly common, at least at several tertiary care institutions. The data and techniques used in pediatric IO are largely extrapolated from experience in adult patients. The management of pediatric tumors differs from that in adults in several categories, such as, the curative intent of treatment, wide use of general anesthesia, aggressive pain management, potentially longer hospital stay, variation in chemotherapy dosing etc. Additionally, pediatric cancers are managed by protocols directed by national and international oncology groups such as the Children's Oncology Group (COG). Consequently, the translation and adoption of these techniques is gradual, but there is a noticeable uptrend due to the growing need. This review will update the current endovascular IO treatments for common pediatric liver, renal, bone and soft tissue tumors.

摘要

至少在几家三级医疗机构中,小儿癌症的介入肿瘤学(IO)治疗需求正变得越来越普遍。小儿IO所使用的数据和技术很大程度上是从成人患者的经验中推断出来的。小儿肿瘤的管理在几个方面与成人不同,例如治疗的治愈意图、全身麻醉的广泛使用、积极的疼痛管理、可能更长的住院时间、化疗剂量的差异等。此外,小儿癌症由国家和国际肿瘤学组织(如儿童肿瘤学组(COG))指导的方案进行管理。因此,这些技术的转化和应用是渐进的,但由于需求不断增长,有明显的上升趋势。本综述将更新目前针对常见小儿肝脏、肾脏、骨骼和软组织肿瘤的血管内IO治疗方法。

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本文引用的文献

1
Clinical characteristics and risk factors of 47 cases with ruptured neuroblastoma in children.儿童破裂型神经母细胞瘤 47 例临床特征及危险因素分析。
BMC Cancer. 2020 Mar 23;20(1):243. doi: 10.1186/s12885-020-06720-9.
2
Selective Arterial Embolization for Large or Symptomatic Renal Angiomyolipoma: 10 Years of Follow-up.选择性动脉栓塞治疗大型或有症状的肾血管平滑肌脂肪瘤:10 年随访结果。
Urology. 2020 Jan;135:82-87. doi: 10.1016/j.urology.2019.09.035. Epub 2019 Oct 13.
3
Intra-arterial chemotherapy in retinoblastoma - A paradigm change.
经动脉化疗栓塞术(TACE)治疗的肝母细胞瘤患者的供血动脉特征及强化模式:数字减影血管造影评估
Narra J. 2023 Dec;3(3):e209. doi: 10.52225/narra.v3i3.209. Epub 2023 Oct 3.
4
Embolization in Pediatric Patients: A Comprehensive Review of Indications, Procedures, and Clinical Outcomes.儿科患者的栓塞治疗:适应症、操作及临床结果的综合综述
J Clin Med. 2022 Nov 8;11(22):6626. doi: 10.3390/jcm11226626.
5
Paediatric IR: the evidence for best practice is growing.儿科介入放射学:最佳实践的证据正在不断增加。
CVIR Endovasc. 2021 Jan 6;4(1):8. doi: 10.1186/s42155-020-00201-7.
眼内动脉化疗治疗视网膜母细胞瘤——一种范式转变。
Indian J Ophthalmol. 2019 Jun;67(6):740-754. doi: 10.4103/ijo.IJO_866_19.
4
Preoperative selective embolization with vascular coiling of giant sacrococcygeal teratoma.巨大骶尾部畸胎瘤的术前选择性血管内栓塞联合弹簧圈栓塞术。
J Neonatal Perinatal Med. 2019;12(3):345-349. doi: 10.3233/NPM-180066.
5
Transarterial radioembolization with yttrium-90 of unresectable primary hepatic malignancy in children.儿童不可切除的原发性肝恶性肿瘤的钇-90 动脉内放射栓塞治疗。
Pediatr Blood Cancer. 2019 Jul;66(7):e27510. doi: 10.1002/pbc.27510. Epub 2018 Nov 8.
6
Pediatric Solid Tumors in Children and Adolescents: An Overview.儿童和青少年的实体瘤:概述
Pediatr Rev. 2018 Sep;39(9):444-453. doi: 10.1542/pir.2017-0268.
7
Doxorubicin-Eluting Intra-Arterial Therapy for Pediatric Extra-Abdominal Desmoid Fibromatoses: A Promising Approach for a Perplexing Disease.多柔比星动脉内洗脱疗法治疗小儿腹外硬纤维瘤:治疗这一棘手疾病的一种有前景的方法
J Vasc Interv Radiol. 2018 Oct;29(10):1376-1382. doi: 10.1016/j.jvir.2018.04.009. Epub 2018 Jul 31.
8
Transarterial chemoembolization in children to treat unresectable hepatocellular carcinoma.儿童经动脉化疗栓塞术治疗不可切除的肝细胞癌。
Pediatr Transplant. 2018 Jun;22(4):e13187. doi: 10.1111/petr.13187. Epub 2018 Apr 29.
9
Right trisegmentectomy after portal vein embolization in a high-risk toddler with hepatoblastoma.肝母细胞瘤高危幼儿门静脉栓塞后门静脉右三叶切除术
Pediatr Surg Int. 2018 May;34(5):573-578. doi: 10.1007/s00383-018-4250-4. Epub 2018 Mar 29.
10
Role of interventional radiology in managing pediatric liver tumors : Part 1: Endovascular interventions.介入放射学在小儿肝脏肿瘤治疗中的作用:第1部分:血管内介入治疗
Pediatr Radiol. 2018 Apr;48(4):555-564. doi: 10.1007/s00247-018-4068-1. Epub 2018 Jan 23.