• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Immunocytochemical localization of a gastric imhibitory polypeptide-like material within A-cells of the endocrine pancreas.

作者信息

Smith P H, Merchant F W, Johnson D G, Fujimoto W Y, Williams R H

出版信息

Am J Anat. 1977 Aug;149(4):585-90. doi: 10.1002/aja.1001490410.

DOI:10.1002/aja.1001490410
PMID:333896
Abstract

In rat pancreatic islets, the glucagon-producing A-cells also contain a GIP-like material as revealed by the peroxidase-antiperoxidase immunocytochemical technique. Control studies showed that this dual staining was not due to the cross-reactivity of anti-GIP with glucagon. It is concluded either that the A-cells synthesize a GIP-like peptide or that it is taken up from the circulation.

摘要

相似文献

1
Immunocytochemical localization of a gastric imhibitory polypeptide-like material within A-cells of the endocrine pancreas.
Am J Anat. 1977 Aug;149(4):585-90. doi: 10.1002/aja.1001490410.
2
Immunocytochemical localization of glucagonlike and gastric inhibitory polypeptidelike peptides in the pancreatic islets and gastrointestinal tract.胰高血糖素样肽和胃抑制性多肽样肽在胰岛和胃肠道中的免疫细胞化学定位。
Am J Anat. 1983 Sep;168(1):109-18. doi: 10.1002/aja.1001680111.
3
Immunocytochemical localization of hormone-producing cells within the pancreatic islets of the rainbow trout (Salmo gairdneri).虹鳟(Salmo gairdneri)胰岛内产生激素细胞的免疫细胞化学定位。
Cell Tissue Res. 1981;221(1):181-92. doi: 10.1007/BF00216580.
4
Gastric inhibitory polypeptide (GIP) and insulin release in the obese Zucker rat.肥胖型 Zucker 大鼠中胃抑制多肽(GIP)与胰岛素释放
Diabetes. 1984 Jun;33(6):536-42. doi: 10.2337/diab.33.6.536.
5
GIP, incretin and gastrointestinal disease.胃抑肽、肠促胰岛素与胃肠疾病
Dan Med Bull. 1983 Jun;30(4):205-14.
6
Electron microscopic immunocytochemical localization of glucagon and pancreatic polypeptide in rat pancreas: characterization of a population of islet cells containing both peptides.大鼠胰腺中胰高血糖素和胰多肽的电子显微镜免疫细胞化学定位:对同时含有这两种肽的胰岛细胞群的特性研究
Anat Rec. 1985 Jul;212(3):292-300. doi: 10.1002/ar.1092120312.
7
The incretin hormones GIP and GLP-1 in diabetic rats: effects on insulin secretion and small bowel motility.糖尿病大鼠体内的肠促胰岛素激素GIP和GLP-1:对胰岛素分泌和小肠蠕动的影响。
Neurogastroenterol Motil. 2009 Mar;21(3):313-21. doi: 10.1111/j.1365-2982.2008.01229.x. Epub 2008 Dec 18.
8
The biology of incretin hormones.肠促胰岛素激素的生物学
Cell Metab. 2006 Mar;3(3):153-65. doi: 10.1016/j.cmet.2006.01.004.
9
GIP-like immunoreactivity in glucagon cells. Interactions between GIP and glucagon on insulin release.胰高血糖素细胞中的GIP样免疫反应性。GIP与胰高血糖素在胰岛素释放上的相互作用。
Acta Physiol Scand. 1981 Jul;112(3):233-42. doi: 10.1111/j.1748-1716.1981.tb06811.x.
10
Gastric inhibitory peptide-like immunoreactivity in glucagon and glicentin cells: properties and origin. An immunocytochemical study using several antisera.
J Histochem Cytochem. 1983 Jun;31(6):811-7. doi: 10.1177/31.6.6188783.

引用本文的文献

1
Glucose-dependent insulinotropic polypeptide (GIP).葡萄糖依赖性促胰岛素多肽(GIP)。
Mol Metab. 2025 May;95:102118. doi: 10.1016/j.molmet.2025.102118. Epub 2025 Feb 28.
2
Establishment of novel specific assay for short-form glucose-dependent insulinotropic polypeptide and evaluation of its secretion in nondiabetic subjects.新型短链葡萄糖依赖性胰岛素促分泌多肽特异性检测方法的建立及其在非糖尿病患者中分泌情况的评估。
Physiol Rep. 2020 Jun;8(11):e14469. doi: 10.14814/phy2.14469.
3
Alternative form of glucose-dependent insulinotropic polypepide and its physiology.
葡萄糖依赖性胰岛素促分泌多肽的另一种形式及其生理学。
J Diabetes Investig. 2016 Apr;7 Suppl 1(Suppl 1):33-7. doi: 10.1111/jdi.12445. Epub 2016 Mar 14.
4
Immunoreactivities of gastrin (G-) cells. II. Non-specific binding of immunoglobulins to G-cells by ionic interactions.胃泌素(G-)细胞的免疫反应性。II. 免疫球蛋白通过离子相互作用与G细胞的非特异性结合。
Histochemistry. 1980;66(2):149-67. doi: 10.1007/BF00494642.
5
Consequences of ventromedial hypothalamic lesions upon insulin and glucagon secretion by subsequently isolated perfused pancreases in the rat.大鼠下丘脑腹内侧核损伤对随后分离的灌注胰腺胰岛素和胰高血糖素分泌的影响。
J Clin Invest. 1980 Apr;65(4):902-10. doi: 10.1172/JCI109744.
6
Immunohistochemical identification of factor X-like antigen in the A cells of the normal human pancreas.正常人胰腺A细胞中X因子样抗原的免疫组织化学鉴定
Diabetologia. 1982 Sep;23(3):255-60. doi: 10.1007/BF00252851.
7
Ultrastructural localization of secretin in endocrine cells of the dog duodenum by the immunogold technique. Comparison with ultrastructurally characterized S cells of various mammals.应用免疫金技术对狗十二指肠内分泌细胞中促胰液素进行超微结构定位。与不同哺乳动物超微结构特征明确的S细胞进行比较。
Histochemistry. 1984;80(5):435-41. doi: 10.1007/BF00495431.
8
Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa.胃抑肽(GIP)在犬十二指肠黏膜特征明确的内分泌细胞中的超微结构定位。
Histochemistry. 1984;80(1):85-9. doi: 10.1007/BF00492776.
9
Clinical aspects of GIP secretion.胃抑肽分泌的临床方面。
Acta Diabetol Lat. 1982 Jan-Mar;19(1):1-11. doi: 10.1007/BF02581180.
10
Immunocytochemical localization of hormone-producing cells within the pancreatic islets of the rainbow trout (Salmo gairdneri).虹鳟(Salmo gairdneri)胰岛内产生激素细胞的免疫细胞化学定位。
Cell Tissue Res. 1981;221(1):181-92. doi: 10.1007/BF00216580.