胃抑肽（GIP）在犬十二指肠黏膜特征明确的内分泌细胞中的超微结构定位。
Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa.
作者信息
Usellini L, Capella C, Solcia E, Buchan A M, Brown J C
出版信息
Histochemistry. 1984;80(1):85-9. doi: 10.1007/BF00492776.
PMID:6365854
Abstract
The polypeptide hormone GIP has been localized ultrastructurally by using specific, monoclonal GIP antibodies and an immunogold technique on aldehyde-osmium fixed specimens of dog duodenal mucosa. A single type of cell showing round, homogeneous, fairly osmiophilic granules with closely applied membrane and a mean size of 188 nm +/- 34 SD has been identified as the GIP cell.
摘要
利用特异性单克隆GIP抗体和免疫金技术，在经醛锇固定的犬十二指肠黏膜标本上，对多肽激素GIP进行了超微结构定位。已鉴定出一种单一类型的细胞，其显示出圆形、均匀、相当嗜锇的颗粒，颗粒膜紧密贴合，平均大小为188纳米±34标准差，该细胞即为GIP细胞。
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