University of Piemonte Orientale, DiSIT- Dipartimento di Scienze e Innovazione Tecnologica, viale Teresa Michel 11, 15121 Alessandria, Italy.
Mini Rev Med Chem. 2021;21(13):1692-1700. doi: 10.2174/1389557521999201230200813.
The Mediterranean diet (MD) is becoming a milestone for the prevention of chronic diseases, such as cardiovascular diseases (CVDs), Alzheimer's and Parkinson's disease. Ancel Keys in the 1950's showed a low mortality rate, particularly for coronary heart disease, among people resident in the Mediterranean area. The MD is characterized by the intake of the high amount of vegetables, fruit, and cereals and regular but moderate consumption of wine, fish, and dairy products, while olive oil is the main source of culinary fat. Therefore, it is principally a plant-based diet rich in polyphenols, a heterogeneous category of compounds with different properties and bioavailabilities. Among polyphenols, anthocyanins have been combined into the human food regime for centuries. They have been utilized as traditional herbal remedies for their ability to treat several conditions, as potent anti-oxidants, anti-diabetic and anti-carcinogenic compounds. This review summarizes our knowledge on the health-enhancing component of the anthocyanins-rich diet.
地中海饮食（Mediterranean diet，MD）正在成为预防慢性疾病（如心血管疾病、阿尔茨海默病和帕金森病）的里程碑。安塞尔·基斯（Ancel Keys）在 20 世纪 50 年代发现，居住在地中海地区的人群死亡率较低，特别是冠心病的死亡率较低。地中海饮食的特点是大量摄入蔬菜、水果和谷物，以及定期但适量地食用葡萄酒、鱼和奶制品，而橄榄油是烹饪脂肪的主要来源。因此，它主要是一种基于植物的饮食，富含多酚，多酚是一类具有不同特性和生物利用度的异类化合物。在多酚中，花青素已经被纳入人类的饮食体系中长达几个世纪。它们一直被用作传统的草药疗法，因为它们具有治疗多种疾病的能力，是一种有效的抗氧化剂、抗糖尿病和抗癌化合物。这篇综述总结了我们对富含花青素饮食的健康增强成分的认识。
