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林(Lam)及其在免疫紊乱中的治疗作用。

Lam and its Therapeutic Effects in Immune Disorders.

作者信息

Xiao Xiao, Wang Jue, Meng Chen, Liang Weibo, Wang Tao, Zhou Bin, Wang Yanyun, Luo Xiaolei, Gao Linbo, Zhang Lin

机构信息

Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University and the Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University, Chengdu, China.

Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.

出版信息

Front Pharmacol. 2020 Dec 17;11:566783. doi: 10.3389/fphar.2020.566783. eCollection 2020.

DOI:10.3389/fphar.2020.566783
PMID:33390944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7773658/
Abstract

Lam., a plant native to tropical forests of India, is characterized by its versatile application as a food additive and supplement therapy. Accumulating evidence shows that plays a critical role in immune-related diseases. In this review, we cover the history, constituents, edibility, and general medicinal value of Moringa. The effects of Moringa in treating immune disorders are discussed in detail. Moringa can not only eliminate pathogens, including bacteria, fungi, viruses, and parasites, but also inhibit chronic inflammation, such as asthma, ulcerative colitis, and metabolic diseases. Additionally, Moringa can attenuate physical and chemical irritation-induced immune disorders, such as metal intoxication, drug side effects, or even the adverse effect of food additives. Autoimmune diseases, like rheumatoid arthritis, atopic dermatitis, and multiple sclerosis, can also be inhibited by Moringa. Collectively, Moringa, with its multiple immune regulatory bioactivities and few side effects, has a marked potential to treat immune disorders.

摘要

辣木是一种原产于印度热带森林的植物,其特点是作为食品添加剂和补充疗法具有多种用途。越来越多的证据表明,它在免疫相关疾病中起着关键作用。在这篇综述中,我们涵盖了辣木的历史、成分、可食用性和一般药用价值。详细讨论了辣木在治疗免疫紊乱方面的作用。辣木不仅可以消除病原体,包括细菌、真菌、病毒和寄生虫,还可以抑制慢性炎症,如哮喘、溃疡性结肠炎和代谢性疾病。此外,辣木可以减轻物理和化学刺激引起的免疫紊乱,如金属中毒、药物副作用,甚至食品添加剂的不良反应。自身免疫性疾病,如类风湿性关节炎、特应性皮炎和多发性硬化症,也可以被辣木抑制。总的来说,辣木有多种免疫调节生物活性且副作用少,在治疗免疫紊乱方面具有显著潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d40/7773658/dbc2f022bdf8/fphar-11-566783-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d40/7773658/dbc2f022bdf8/fphar-11-566783-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d40/7773658/dbc2f022bdf8/fphar-11-566783-g001.jpg

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Moringa oleifera seed oil or virgin coconut oil supplementation abrogates cerebral neurotoxicity induced by antineoplastic agent methotrexate by suppression of oxidative stress and neuro-inflammation in rats.
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