Furtado Guilherme Eustáquio, Letieri Rubens Vinícius, Caldo-Silva Adriana, Sardão Vilma A, Teixeira Ana Maria, de Barros Marcelo Paes, Vieira Rodolfo Paula, Bachi André Luís Lacerda
Health Sciences Research Unit, Nursing (UICISA:E), Nursing School of Coimbra (ESEnfC), Coimbra, Portugal.
N2i - Polytechnic Institute of Maia, Maia, Portugal.
Eur J Clin Invest. 2021 May;51(5):e13485. doi: 10.1111/eci.13485. Epub 2021 Feb 9.
The new coronavirus (SARS-CoV-2) appearance in Wuhan, China, did rise the new virus disease (COVID-19), which spread globally in a short time, leading the World Health Organization to declare a new global pandemic. To contain and mitigate the spread of SARS-CoV-2, specific public health procedures were implemented in virtually all countries, with a significant impact on society, making it difficult to keep the regular practice of physical activity. It is widely accepted that an active lifestyle contributes to the improvement of general health and preservation of cardiovascular, respiratory, osteo-muscular and immune system capacities. The positive effects of regular physical activity on the immune system have emerged as a pivotal trigger of general health, underlying the beneficial effects of physical activity on multiple physiological systems. Accordingly, recent studies have already pointed out the negative impact of physical inactivity caused by the social isolation imposed by the public sanitary authorities due to COVID-19. Nevertheless, there are still no current narrative reviews evaluating the real impact of COVID-19 on active lifestyle or even discussing the possible beneficial effects of exercise-promoted immune upgrade against the severity or progression of COVID-19. Based on the consensus in the scientific literature, in this review, we discuss how an exercise adherence could adequately improve immune responses in times of the 'COVID-19 Era and beyond'.
新型冠状病毒（SARS-CoV-2）在中国武汉出现，引发了新型病毒性疾病（COVID-19），该疾病在短时间内蔓延至全球，导致世界卫生组织宣布全球进入新的大流行状态。为了遏制和减轻SARS-CoV-2的传播，几乎所有国家都实施了特定的公共卫生程序，这对社会产生了重大影响，使得维持日常体育活动变得困难。人们普遍认为，积极的生活方式有助于改善总体健康状况，并维护心血管、呼吸、骨肌肉和免疫系统的功能。定期进行体育活动对免疫系统的积极影响已成为总体健康的关键触发因素，这也凸显了体育活动对多个生理系统的有益作用。因此，最近的研究已经指出，由于COVID-19，公共卫生当局实施的社会隔离措施导致身体不活动所产生的负面影响。然而，目前仍没有叙述性综述评估COVID-19对积极生活方式的实际影响，甚至没有讨论运动促进的免疫提升对COVID-19严重程度或病程的可能有益作用。基于科学文献中的共识，在本综述中，我们讨论了在“COVID-19时代及以后”，坚持运动如何能够充分改善免疫反应。
