Department of Physical Education, Catholic University of Brasilia (UCB).
Department of Gerontology, Catholic University of Brasilia, UCB, Brasilia.
Blood Press Monit. 2021 Apr 1;26(2):135-145. doi: 10.1097/MBP.0000000000000505.
Repeated measures analysis of covariance and three-way analysis of variance with repeated measures are common statistical methods. For a valid interpretation of blood pressure (BP) response to exercise, a variety of additional statistical methods must be implemented. Four additional statistical methods are presented: technical error of measurement (SEM), smallest real difference (SRD), magnitude-based inference and mixed effect modeling technique (MEM). The aim of this perspective article is to demonstrate how to apply already known statistical analyses regarding BP responsiveness in order to improve interpretation and achieve higher reliability for future studies in exercise science.
A total of 27 hypertensive older women (aged 68.37 ± 5.55 years) participated in the present study. A whole-body resistance training (RT) program was performed on two nonconsecutive days per week for 10 weeks. BP was monitored during the 10-week RT intervention and after 15 weeks of detraining. First, individuals were classified as high and low responders, then statistical methods to analyze data included the use of SEM, SRD, magnitude-based inference and MEM.
When magnitude-based inference was used to classify responsiveness, most participants displayed a trivial response. Decrements in SBP between 1 and 10 mmHg were not clinically meaningful but fell within the measurement error of the SBP measurements. Baseline SBP and time of training predicted post-SBP response.
Changes over time and declines in SBP might not be a SRD and fell in the SEM. Moreover, SBP responsiveness was the result of inappropriate control of covariates such as period of training.
重复测量协方差分析和三向重复测量方差分析是常见的统计方法。为了有效解释运动对血压（BP）的反应，必须实施各种其他统计方法。本文提出了四种额外的统计方法：测量技术误差（SEM）、最小实际差异（SRD）、基于幅度的推断和混合效应建模技术（MEM）。本文的目的是展示如何应用已经熟知的关于 BP 反应性的统计分析方法，以提高解释能力，并为未来运动科学研究提供更高的可靠性。
共有 27 名高血压老年女性（年龄 68.37 ± 5.55 岁）参加了本研究。每周进行两次非连续的全身抗阻训练（RT），共 10 周。在 10 周 RT 干预期间和 15 周停训后监测 BP。首先，个体被分类为高反应者和低反应者，然后使用 SEM、SRD、基于幅度的推断和 MEM 分析数据的统计方法。
当使用基于幅度的推断来分类反应性时，大多数参与者表现出微不足道的反应。SBP 的降低在 1 到 10mmHg 之间，没有临床意义，但在 SBP 测量的测量误差范围内。SBP 的基线值和训练时间预测了 post-SBP 反应。
随着时间的推移而发生的变化和 SBP 的下降可能不是 SRD，而是落在 SEM 范围内。此外，SBP 的反应性是由于对训练时间等协变量的控制不当所致。
