Sun Wenli, Chen Zican, Hong Jun, Shi Jianxin
Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Biology (Basel). 2020 Dec 31;10(1):20. doi: 10.3390/biology10010020.
Plant metabolomics plays important roles in both basic and applied studies regarding all aspects of plant development and stress responses. With the improvement of living standards, people need high quality and safe food supplies. Thus, understanding the pathways involved in the biosynthesis of nutritionally and healthily associated metabolites in plants and the responses to plant-derived biohazards in humans is of equal importance to meet people's needs. For each, metabolomics has a vital role to play, which is discussed in detail in this review. In addition, the core elements of plant metabolomics are highlighted, researches on metabolomics-based crop improvement for nutrition and safety are summarized, metabolomics studies on plant natural products including traditional Chinese medicine (TCM) for health promotion are briefly presented. Challenges are discussed and future perspectives of metabolomics as one of the most important tools to promote human nutrition and health are proposed.
植物代谢组学在植物发育和应激反应各个方面的基础研究和应用研究中都发挥着重要作用。随着生活水平的提高，人们需要高质量且安全的食物供应。因此，了解植物中与营养和健康相关代谢物的生物合成途径以及人类对植物源性生物危害的反应对于满足人们的需求同样重要。对于这两方面，代谢组学都发挥着至关重要的作用，本综述将对此进行详细讨论。此外，还强调了植物代谢组学的核心要素，总结了基于代谢组学的作物营养与安全改良研究，简要介绍了植物天然产物（包括用于促进健康的中药）的代谢组学研究。讨论了面临的挑战，并提出了代谢组学作为促进人类营养与健康的最重要工具之一的未来前景。
