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开发用于非侵入性小脑刺激的实施和评估的小脑储备评估工具的迫切需求。

The critical need to develop tools assessing cerebellar reserve for the delivery and assessment of non-invasive cerebellar stimulation.

作者信息

Manto Mario, Kakei Shinji, Mitoma Hiroshi

机构信息

Unité des Ataxies Cérébelleuses, Service de Neurologie, CHU-Charleroi, Charleroi, Belgium.

Service des Neurosciences, Université de Mons, Mons, Belgium.

出版信息

Cerebellum Ataxias. 2021 Jan 4;8(1):2. doi: 10.1186/s40673-020-00126-w.

Abstract

Non-invasive cerebellar stimulation (NICS) aims to modulate cerebello-cerebral loops and cerebro-spinal loops, both for research and clinical applications. It is of paramount importance to establish and validate morphological and functional tools to quantify cerebellar reserve, defined as the capacity for restoration and compensation to pathology of the cerebellum. Using NICS without efforts to estimate cerebellar reserve will end up in conflicting results due to the very high heterogeneity of cerebellar disorders encountered in daily practice.

摘要

无创小脑刺激(NICS)旨在调节小脑-大脑环路和脑-脊髓环路,用于研究和临床应用。建立和验证形态学和功能工具以量化小脑储备至关重要,小脑储备被定义为小脑对病理状态的恢复和补偿能力。由于在日常实践中遇到的小脑疾病具有非常高的异质性,如果不努力评估小脑储备就使用NICS,最终将会得到相互矛盾的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55d4/7784008/3d906e97dfd4/40673_2020_126_Fig1_HTML.jpg

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