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磁共振成像在产前胎儿胆囊未显影诊断中的应用:一项病例系列研究

Utility of Magnetic Resonance Imaging in Diagnosis of Prenatal Non-Visualization of the Fetal Gallbladder: A Case-Series Study.

作者信息

Wang Yuanhe, Zhou Jinling, Deng Meixiang, Xiang Xiaomiao, Zhu Xiaojun

机构信息

Department of Obstetrics, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).

Department of Radiology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).

出版信息

Med Sci Monit. 2021 Jan 5;27:e927474. doi: 10.12659/MSM.927474.

DOI:10.12659/MSM.927474
PMID:33397840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7796068/
Abstract

BACKGROUND This study aimed to assess the utility of magnetic resonance imaging (MRI) in the diagnosis of prenatal non-visualization of the fetal gallbladder (PNVGB). MATERIAL AND METHODS The clinical data of 32 pregnant women with PNVGB who underwent MRI examination during the second and third trimester of pregnancy were collected and their outcomes were analyzed. RESULTS MRI showed that 26 patients (81.3%) had isolated PNVGB and 6 (18.8%) had additional malformations. In 26 patients with isolated PNVGB, 7 were found in the gallbladder on MRI and 4 were found on subsequent ultrasonography. One patient had termination of pregnancy (TOP) and 1 patient was lost to follow-up; the remaining 24 patients were known to deliver a healthy child. Among the 6 patients with additional malformations, 3 terminated their pregnancies due to combined severe abnormalities: 1 patient with horseshoe kidney and 1 with fetal echogenic bowel both had a healthy child, while 1 with fetal growth restriction (FGR) delivered a child who walked on tiptoe. CONCLUSIONS MRI contributes to identifying PNVGB detected or suspected by ultrasonography.

摘要

背景 本研究旨在评估磁共振成像(MRI)在产前胎儿胆囊未显影(PNVGB)诊断中的应用价值。材料与方法 收集32例在妊娠中晚期接受MRI检查的PNVGB孕妇的临床资料,并分析其结局。结果 MRI显示,26例患者(81.3%)为孤立性PNVGB,6例(18.8%)合并其他畸形。在26例孤立性PNVGB患者中,MRI发现7例胆囊存在问题,后续超声检查发现4例。1例患者终止妊娠(TOP),1例失访;其余24例患者已知分娩出健康婴儿。在6例合并其他畸形的患者中,3例因合并严重异常而终止妊娠:1例马蹄肾患者和1例胎儿肠管回声增强患者均分娩出健康婴儿,而1例胎儿生长受限(FGR)患者分娩出踮脚走路的婴儿。结论 MRI有助于识别超声检查发现或怀疑的PNVGB。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45d4/7796068/5f8bbca6161e/medscimonit-27-e927474-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45d4/7796068/f040e811c489/medscimonit-27-e927474-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45d4/7796068/5f8bbca6161e/medscimonit-27-e927474-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45d4/7796068/f040e811c489/medscimonit-27-e927474-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45d4/7796068/5f8bbca6161e/medscimonit-27-e927474-g002.jpg

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本文引用的文献

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MRI in the diagnosis of fetal developmental brain abnormalities: the MERIDIAN diagnostic accuracy study.磁共振成像在胎儿发育性脑异常诊断中的应用:MERIDIAN 诊断准确性研究。
Health Technol Assess. 2019 Sep;23(49):1-144. doi: 10.3310/hta23490.
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Outcome of non-visualization of fetal gallbladder on second-trimester ultrasound: cohort study and systematic review of literature.中孕期超声胎儿胆囊未显示的结局:队列研究和文献系统评价。
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Isolated Nonvisualization of the Fetal Gallbladder Should Be Considered for the Prenatal Diagnosis of Cystic Fibrosis.孤立性胎儿胆囊未显影应考虑用于囊性纤维化的产前诊断。
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[Prenatal diagnosis of gallbladder abnormalities: a review].[胆囊异常的产前诊断:综述]
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Accuracy of ultrasonography at 11-14 weeks of gestation for detection of fetal structural anomalies: a systematic review.超声检查在 11-14 孕周检测胎儿结构畸形的准确性:系统评价。
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