Manipal University Jaipur, Rajasthan, 303007, India.
Punjab Engineering College (Deemed to be University), Chandigarh, 160012, India.
IET Nanobiotechnol. 2020 Dec;14(9):858-863. doi: 10.1049/iet-nbt.2019.0348.
In the present investigation, roots extract mediated magnesium hydroxide nanoparticles [Mg(OH) NPs] through the bio-inspired experimental technique were synthesised. Mg(OH) NPs were characterised by using various characterisation techniques such as field emission scanning electron microscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), and ultraviolet-visible spectroscopy. The formation of Mg(OH) NPs was confirmed by X-ray diffraction. The structural analysis confirmed the hexagonal crystal symmetry of Mg(OH) NPs with space group and space group no. 164 using the Rietveld refinement technique. TEM micrographs illustrated the nano-size formation of Mg(OH) NPs of spherical shape and size ∼14.86 nm. With the aid of FTIR data, plant metabolites such as anthraquinones have been identified as a stabilising and reducing agent for the synthesis of biogenic Mg(OH) NPs. The synthesised Mg(OH) NPs showed antimicrobial and cytotoxic potential against Gram-negative and Gram-positive bacteria such as (ATCC 25922) and (ATCC 25923) and MDA-MB-231 human breast cancer cell lines.
在本研究中，通过生物启发的实验技术合成了根提取物介导的氢氧化镁纳米粒子 [Mg(OH) NPs]。使用各种特性分析技术，如场发射扫描电子显微镜、透射电子显微镜（TEM）、傅里叶变换红外光谱（FTIR）和紫外-可见光谱，对 Mg(OH) NPs 进行了表征。X 射线衍射证实了 Mg(OH) NPs 的形成。结构分析使用 Rietveld 精修技术证实了 Mg(OH) NPs 的六方晶体对称性，空间群为 和空间群 No. 164。TEM 显微照片说明了 Mg(OH) NPs 的纳米尺寸形成，呈球形，尺寸约为 14.86nm。借助 FTIR 数据，已鉴定出蒽醌等植物代谢物是合成生物成因 Mg(OH) NPs 的稳定和还原剂。合成的 Mg(OH) NPs 对革兰氏阴性和革兰氏阳性细菌（如 （ATCC 25922）和 （ATCC 25923））和 MDA-MB-231 人乳腺癌细胞系表现出抗菌和细胞毒性潜力。
