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男男性行为者献血:利用证据改变政策。

Blood donation by men who have sex with men: using evidence to change policy.

机构信息

NHS Blood and Transplant/Public Health England Epidemiology Unit, Public Health England, London, UK.

Microbiological Services, NHS Blood and Transplant, London, UK.

出版信息

Vox Sang. 2021 Mar;116(3):260-272. doi: 10.1111/vox.13033. Epub 2021 Jan 5.

DOI:10.1111/vox.13033
PMID:33400285
Abstract

BACKGROUND

In 2011 in the United Kingdom (UK), excluding Northern Ireland, the deferral of men who have sex with men (MSM) changed from lifetime to 12 months. We describe MSM who donated before and after this to inform further policy reviews.

MATERIALS AND METHODS

Characteristics and sexual behaviours of donors identifying as male from routine surveillance are described. Rates of infections are compared pre- and post-implementation of a 12-month deferral. Donors are compared with screen negative male donors responding to a large-scale survey during 2013/2014.

RESULTS

Comparing the five years pre- and post-change, the rate of confirmed positives for markers of HBV, HCV, HIV and syphilis decreased by 6·9% from 14·1 to 13·1/100 000 donations. The rate of recent infections was unchanged (1·72/100 000). Of 22 776 survey responses identifying as male, MSM disclosed sex between men over 12 months ago giving 99·35% compliance among male donors. Two-thirds of the 72 non-compliant MSM reported one to two partners and one-third had no new partners within 12 months. The most commonly reported reason for non-compliance from MSM both positive and negative for infection was 'not important to declare' (37·2% and 40·7%). Test seeking was rare (9·3% and 2·1%).

CONCLUSION

Compliance with the 12-month MSM deferral policy was very high. The very low rates of infections post-change demonstrated the effectiveness of the policy. These data were an important part of the 2017 review of all sexual behaviour deferrals.

摘要

背景

2011 年,在英国(英国),不包括北爱尔兰,男男性行为者(MSM)的延迟从终身改为 12 个月。我们描述了在此之前和之后进行捐赠的 MSM,以进一步告知政策审查。

材料和方法

描述了从常规监测中识别为男性的捐赠者的特征和性行为。比较实施 12 个月延迟前后感染率。将捐赠者与在 2013/2014 年期间对大规模调查做出反应的阴性男性捐赠者进行比较。

结果

比较变更前后的五年,HBV、HCV、HIV 和梅毒标志物的确诊阳性率从 14.1 降至 13.1/100000 次捐赠,下降了 6.9%。最近感染率保持不变(1.72/100000)。在 22776 名识别为男性的调查回复中,有 99.35%的男性捐赠者在 12 个月前报告了与男性之间的性行为。三分之二的 72 名不遵守规定的 MSM 报告了一到两个伴侣,三分之一的人在 12 个月内没有新伴侣。无论是感染阳性还是阴性的 MSM,不遵守规定的最常见原因都是“不重要声明”(分别为 37.2%和 40.7%)。检测寻求很少见(分别为 9.3%和 2.1%)。

结论

遵守 12 个月 MSM 延迟政策的合规率非常高。变更后感染率非常低证明了该政策的有效性。这些数据是 2017 年对所有性行为延迟审查的重要组成部分。

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