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遵守基于中性性行为的献血者筛查问题。

Compliance with gender-neutral sexual behavior-based blood donor screening questions.

作者信息

O'Brien Sheila F, Osmond Lori, Goldman Mindy

机构信息

Epidemiology & Surveillance, Canadian Blood Services, Ottawa, Ontario, Canada.

School of Epidemiology & Public Health, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Transfusion. 2025 Aug;65(8):1451-1459. doi: 10.1111/trf.18302. Epub 2025 Jun 16.

DOI:10.1111/trf.18302
PMID:40524388
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12315639/
Abstract

BACKGROUND

In September 2022, Canadian Blood Services replaced the time-based deferral for gay and bisexual men who have sex with men (gbMSM) with sexual behavior-based questions. All donors who had sex with a new partner or >1 partner in the last 3 months and anal sex were deferred, permitting gbMSM with one regular partner to donate. We aimed to measure compliance with the new criteria post-implementation.

STUDY DESIGN AND METHODS

Pre-implementation 42,999; post-implementation 41,157 donors were invited to complete an anonymous online sexual risks survey. Results were weighted reflecting the donor base age, sex, and geography base. Frequencies and 95% confidence intervals were calculated.

RESULTS

In total, 13,159 donors participated pre-implementation (33% participation, 6532 females and 6627 males of whom 183 had ever had sex with another man (gbMSM)); post-implementation 11,217 donors (28% participation, 5253 females and 5964 males of whom 188 were gbMSM). Pre-implementation 9.3% (4.3%-14.2%) gbMSM had a new or >1 partner and anal sex in the last 3 months (all ineligible), similar to post-implementation when some were eligible (8.9%, 4.1%-13.8%, p > .05). There was no difference between pre- and post-implementation for non-gbMSM males (pre- 0.7%, 0.5%-1.0% vs. post-0.7%, 0.4-0.9) and females (pre- 0.8%, 0.6%-1.0% vs. post-0.6%, 0.4-0.8%) (p > .05). The estimated non-compliance of those with deferrable behavior was 87% (79%-93%). Most donors reported being comfortable with the new questions.

DISCUSSION

The majority of donors with deferrable sexual behaviors failed to disclose post-implementation. Donors may make a judgment about whether they need to disclose behaviors in screening.

摘要

背景

2022年9月,加拿大血液服务中心将针对与男性发生性关系的男同性恋者(gbMSM)基于时间的延期献血政策替换为基于性行为的问题筛查。所有在过去3个月内与新伴侣或超过1名伴侣发生性行为且有肛交行为的献血者均被延期献血,允许只有一名固定伴侣的gbMSM献血。我们旨在评估新标准实施后的依从性。

研究设计与方法

实施前邀请了42999名献血者;实施后邀请了41157名献血者完成一项匿名在线性风险调查。结果根据献血者群体的年龄、性别和地域进行加权。计算了频率和95%置信区间。

结果

实施前共有13159名献血者参与(参与率33%,女性6532名,男性6627名,其中183名曾与另一名男性发生过性行为(gbMSM));实施后有11217名献血者参与(参与率28%,女性5253名,男性5964名,其中188名是gbMSM)。实施前9.3%(4.3%-14.2%)的gbMSM在过去3个月内有新伴侣或超过1名伴侣且有肛交行为(均不符合献血条件),与实施后情况类似,实施后部分人符合条件(8.9%,4.1%-13.8%,p>0.05)。实施前后非gbMSM男性(实施前0.7%,0.5%-1.0%;实施后0.7%,0.4-0.9)和女性(实施前0.8%,0.6%-1.0%;实施后0.6%,0.4-0.8%)之间无差异(p>0.05)。有可延期行为者的估计不依从率为87%(79%-93%)。大多数献血者表示对新问题感到满意。

讨论

大多数有可延期性行为的献血者在实施后未披露相关情况。献血者可能会自行判断在筛查中是否需要披露行为。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/7f29d2281c17/TRF-65-1451-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/627a441d5977/TRF-65-1451-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/327cec1d7f3c/TRF-65-1451-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/8a25b221dfa6/TRF-65-1451-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/7f29d2281c17/TRF-65-1451-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/627a441d5977/TRF-65-1451-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/327cec1d7f3c/TRF-65-1451-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/8a25b221dfa6/TRF-65-1451-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1773/12315639/7f29d2281c17/TRF-65-1451-g003.jpg

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本文引用的文献

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Transfusion. 2024 Jul;64(7):1254-1261. doi: 10.1111/trf.17878. Epub 2024 May 17.
2
Evolving the gay, bisexual and other men who have sex with men time-based deferral to sexual risk screening for all donors: The contribution of Canadian research programmes.不断变化的男同性恋、双性恋和其他与男性发生性关系的男性基于时间的延迟,对所有供体进行性风险筛查:加拿大研究计划的贡献。
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Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data.
取消男男性行为者献血暂缓:利用加拿大公共卫生监测数据为风险模型提供信息。
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Transfusion. 2022 Jan;62(1):125-134. doi: 10.1111/trf.16753. Epub 2021 Dec 1.
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