Postgraduate School of Paediatrics, Department of Clinical and Experimental Medicine, Section of Paediatric, University of Pisa, 56126 Pisa, Italy.
Pediatric Hematology Oncology, Bone Marrow Transplant, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.
Int J Environ Res Public Health. 2021 Jan 2;18(1):283. doi: 10.3390/ijerph18010283.
A boy affected by autism spectrum disorder was admitted for persistent high fever, without shiver, for two weeks. The boy referred to abdominal pain, in the first week of fever, and to mild anorexia in the last days before admittance to our hospital centre. The father reported that the boy suffered by geophagia and coprophagia and he has been going to a didactical farm (where he has been exposed to several kinds of animals) to improve his neuropsychiatric condition. Blood analysis shows severe eosinophilia and high levels of total IgE, and abdominal echocardiography showed hepatic lesions. Enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) confirmed the suspicion of toxocariasis, linked to the habit of the boy to ingest ground or animal faeces in a didactic farm frequented by the boy. Treatment with albendazole and prednisone was administered with a rapid improvement of the symptoms and the laboratory findings and significant reduction of the hepatic lesion.
一名患有自闭症谱系障碍的男孩因持续高热（无寒战）两周而入院。男孩自述腹痛，在发热的第一周，并在入我院前的最后几天出现轻度食欲不振。父亲报告说，男孩患有食土癖和食粪癖，他一直在一家教学农场（在那里他接触了几种动物），以改善他的神经精神状况。血液分析显示严重的嗜酸性粒细胞增多和总 IgE 水平升高，腹部超声心动图显示肝脏病变。酶联免疫吸附试验（ELISA）和 Western blot（WB）证实了对旋毛虫病的怀疑，这与男孩在一家教学农场的习惯有关，该农场常接触地面或动物粪便。给予阿苯达唑和泼尼松治疗后，症状和实验室检查迅速改善，肝脏病变明显减轻。
