Department of Infectious Diseases and Clinical Microbiology, Duzce University Faculty of Medicine, Duzce, Turkey.
Duzce University Research and Application Hospital, Infection Control Committee Nurse Duzce, Turkey.
Afr Health Sci. 2020 Sep;20(3):1118-1123. doi: 10.4314/ahs.v20i3.13.
is a Gram-negative bacillus and opportunistic emergent pathogen causing hospital-acquired infections (HAIs). Due to risk factors such as prolonged intensive care unit stay and invasive procedures, it has become one of the leading causes of HAIs.
The aim of this study was to evaluate the epidemiology of infections over a six-year period at Düzce University Hospital, Turkey.
The incidence, clinical characteristics, antimicrobial susceptibility and outcomes of nosocomial infections during this period were retrospectively analyzed.
During the study period, 67 samples obtained from 61 patients were identified. Pneumonias (82%) were the most common HAIs, followed by bloodstream infections (10.5%), urinary tract infections (3%), skin and soft tissue infections (3%) and surgical site infection (1.5%). Admission to intensive care, hospitalization exceeding 30 days, and previous use of broad-spectrum antibiotics constituted risk factors. Resistance to cotrimoxazole (6%) was lower than that to levofloxacin (18%).
The most important risk factors for infection in patients are previous exposure to antibiotics, prolonged hospitalization and invasive procedures such as mechanic ventilation. Discharging patients as early as possible with the rational use of antibiotics may be effective in reducing infections and resistance rates.
是一种革兰氏阴性杆菌，也是一种机会性新兴病原体，可导致医院获得性感染（HAIs）。由于长时间入住重症监护病房和进行有创操作等风险因素，它已成为导致 HAI 的主要原因之一。
本研究旨在评估土耳其迪兹杰大学医院六年来感染的流行病学情况。
回顾性分析了在此期间发生的医院获得性感染的发病率、临床特征、抗菌药物敏感性和转归。
在研究期间，从 61 名患者中分离出 67 株样本。肺炎（82%）是最常见的 HAI，其次是血流感染（10.5%）、尿路感染（3%）、皮肤软组织感染（3%）和手术部位感染（1.5%）。入住重症监护病房、住院时间超过 30 天和之前使用广谱抗生素是危险因素。与左氧氟沙星（18%）相比，对复方磺胺甲噁唑的耐药率（6%）较低。
抗生素暴露史、住院时间延长和有创操作（如机械通气）是患者感染的最重要危险因素。尽早出院并合理使用抗生素可能有助于降低感染和耐药率。
