Departments of Microbiology & Immunology, National University of Science and Technology, Sohar, Oman.
Department of Epidemiology and Public Health, All India Institute of Medical Sciences, Mangalgiri, India.
Sultan Qaboos Univ Med J. 2021 Feb;21(1):e66-e71. doi: 10.18295/squmj.2021.21.01.009. Epub 2021 Mar 15.
, a Gram-negative non-fermentative bacillus, has emerged as an important nosocomial pathogen in recent years. It is intrinsically resistant to many antibiotics and has the ability to acquire antibiotic resistance by multiple mechanisms. Treating infections, therefore, is a serious challenge for physicians. This study aimed to investigate the antibiotic susceptibility patterns and risk factors contributing to infections.
A retrospective cross-sectional study was conducted at Sohar Hospital in Sohar, Oman. The demographic, clinical and microbiological data of individuals from whom was isolated between September 2016 and August 2019 were reviewed. Descriptive statistics were presented as frequencies and percentages.
A total of 41 isolates from clinical specimens of 41 patients were studied. Infection occurred predominantly in males (73%) and the majority of patients (88%) were either ≤5 years old or >60 years old. All inpatients had at least one comorbidity while 50% had more than one. All inpatients were exposed to various medical interventions such as intensive care (44%), mechanical ventilation (41%), haemodialysis (25%), Foley's catheterisation (13%) and central venous lines (6%). Most patients (81%) were in hospital longer than two weeks. The susceptibility rates of to minocycline (97%), trimethoprim-sulfamethoxazole (93%) and levofloxacin (92%) were high; the rate was lowest for ceftazidime (50%).
was found to be an important nosocomial opportunistic pathogen. Prolonged hospital stay and exposure to various medical interventions were key factors contributing to the development of infection. Minocycline and ceftazidime were found to be the most and least susceptible drugs, respectively.
是一种革兰氏阴性非发酵杆菌，近年来已成为一种重要的医院获得性病原体。它对许多抗生素具有内在抗性，并具有通过多种机制获得抗生素抗性的能力。因此，治疗 感染是医生面临的严峻挑战。本研究旨在调查 感染的抗生素敏感性模式和相关危险因素。
在阿曼苏哈尔医院进行了一项回顾性横断面研究。对 2016 年 9 月至 2019 年 8 月期间从分离出 的个体的人口统计学、临床和微生物学数据进行了回顾性分析。采用描述性统计方法表示为频率和百分比。
共研究了来自 41 例患者临床标本的 41 株 分离株。感染主要发生在男性（73%）中，大多数患者（88%）年龄≤5 岁或>60 岁。所有住院患者至少有一种合并症，而 50%的患者有多种合并症。所有住院患者都接受了各种医疗干预，如重症监护（44%）、机械通气（41%）、血液透析（25%）、 Foley 导管插入术（13%）和中心静脉置管（6%）。大多数患者（81%）住院时间超过两周。 对米诺环素（97%）、复方磺胺甲噁唑（93%）和左氧氟沙星（92%）的敏感性较高；头孢他啶的敏感性最低（50%）。
被发现是一种重要的医院获得性机会性病原体。长时间住院和接受各种医疗干预是导致感染发生的关键因素。米诺环素和头孢他啶分别是最敏感和最不敏感的药物。
