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南非马丹萨恩镇农村地区资源受限患者的糖尿病和高血压的社会人口学和可改变风险因素。

Socio-demographic and modifiable risk factors of diabetes and hypertension among resource constrained patients from rural areas in Mdantsane Township in South Africa.

机构信息

Precision Medicine Unit, Department of Biotechnology, Faculty of Natural Sciences, University of the Western Cape, Robert Sobukwe Road, Bellville, 7535, South Africa.

Department of Family Medicine, Walter Sisulu University, East London, South Africa.

出版信息

Afr Health Sci. 2020 Sep;20(3):1344-1354. doi: 10.4314/ahs.v20i3.41.

Abstract

BACKGROUND

Recently, developing countries have shown a dramatic increase in non-communicable diseases (NCDs). The burden of NCDs in South Africa has increased over the past years resulting in an estimated 37% of all- cause mortality and 16% of disability-adjusted life years. Currently, diabetes mellitus (DM) and hypertension (HTN) are the two most prevalent NCDs associated with the rapid increase in mortality.

OBJECTIVE

To demonstrate the socio-demographic and modifiable risk factors of diabetes mellitus (DM) and hypertension (HTN) among South African adults.

METHODS

A cross-sectional analytical study was conducted in the Cecilia Makiwane Hospital serving the residents of Mdantsane. Relevant socio-demographic data, anthropometric measurements, triplicate blood pressure, fasting blood glucose and lipogram analysis were obtained from 265 outpatients.

RESULTS

Multivariate anlysis shows that; salt intake, smoking, elevated triglycerides and decreased high-density lipoprotein levels were significantly associated with DM with adjusted odds ratio of 0.18 (p=0.002), 0.26 (p=0.048), 2.19 (p=0.006) and 0.38 (p=0.001), respectively. Overweight and obesity were significantly associated with hypertension with odds ratio of 0.03 (p=0.01) and 0.06 (p=0.006), respectively.

CONCLUSION

The burden of DM and HTN on society can be drastically reduced with simple lifestyle changes, development of preventative strategies, large-scale screening and better disease management in South Africa.

摘要

背景

最近,发展中国家的非传染性疾病(NCDs)发病率显著上升。南非的 NCD 负担在过去几年中有所增加,导致估计有 37%的全因死亡率和 16%的伤残调整生命年。目前,糖尿病(DM)和高血压(HTN)是与死亡率迅速上升相关的两种最常见的 NCD。

目的

展示南非成年人中糖尿病(DM)和高血压(HTN)的社会人口统计学和可改变的危险因素。

方法

在为 Mdantsane 居民服务的 Cecilia Makiwane 医院进行了一项横断面分析性研究。从 265 名门诊患者中获得了相关的社会人口统计学数据、人体测量学测量值、三次血压、空腹血糖和血脂分析。

结果

多变量分析显示,盐摄入量、吸烟、甘油三酯升高和高密度脂蛋白水平降低与 DM 显著相关,调整后的优势比分别为 0.18(p=0.002)、0.26(p=0.048)、2.19(p=0.006)和 0.38(p=0.001)。超重和肥胖与高血压显著相关,优势比分别为 0.03(p=0.01)和 0.06(p=0.006)。

结论

通过简单的生活方式改变、制定预防策略、大规模筛查和更好的疾病管理,可以大大减轻南非 DM 和 HTN 给社会带来的负担。

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Standards of medical care in diabetes--2014.2014年糖尿病医疗护理标准
Diabetes Care. 2014 Jan;37 Suppl 1:S14-80. doi: 10.2337/dc14-S014.

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