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南非埃特科姆区医院 HIV 阳性人群中糖尿病和高血压的患病率。

Prevalence of diabetes mellitus and hypertension amongst the HIV-positive population at a district hospital in eThekwini, South Africa.

机构信息

Discipline of Family Medicine, Faculty of Health Sciences, University of KwaZulu-Natal, Durban.

出版信息

Afr J Prim Health Care Fam Med. 2021 Sep 29;13(1):e1-e6. doi: 10.4102/phcfm.v13i1.2766.

Abstract

BACKGROUND

Life expectancies of HIV-positive patients have been increasing with the rapid implementation of antiretroviral therapy (ART). This has led to an increase in comorbidities such as diabetes mellitus (DM) and hypertension (HT) amongst the HIV population. The burden of the non-communicable diseases (NCDs) such as DM and HT need to be quantified in order to ensure that patients receive optimal integrated care as patients often access care at different clinics compromising holistic care.

AIM

The aim of the study was to determine the prevalence of DM and HT amongst the HIV-positive population.

SETTING

The study was conducted at Wentworth Hospital, a district facility in South Durban, KwaZulu-Natal.

METHODS

This cross-sectional study was undertaken to determine the prevalence of two NCDs, namely DM and HT in HIV-positive patients attending the ART clinic at a district hospital in the eThekwini district. We compared the socio-demographic and clinical profiles of those with and without comorbidities. A sample of 301 HIV-positive patients were administered a structured questionnaire.

RESULTS

Of the 301 patients, 230 (76.41%) had HIV only (95% confidence interval [CI]: 71.25-80.89) and 71 (23.59%) had HIV and at least one comorbidity, namely DM and/or HT (95% CI: 19.11-28.75). Hypertension was the most prevalent comorbidity. This study revealed that there was no association between the duration of ART and comorbidities. Older age and body mass index (BMI) were associated with comorbidities, whilst gender and ethnicity were not associated.

CONCLUSION

Non-communicable diseases such as DM and HT do pose a burden for HIV-positive patients attending the ARV clinic at this district facility. This study highlights the definite need to plan for the increased burden of NCDs as HIV-positive patients live longer and gain weight.

摘要

背景

随着抗逆转录病毒疗法(ART)的迅速实施,艾滋病毒感染者的预期寿命不断延长。这导致艾滋病毒感染者中出现了更多的合并症,如糖尿病(DM)和高血压(HT)。为了确保患者接受最佳的综合护理,需要对非传染性疾病(NCDs)的负担进行量化,因为患者经常在不同的诊所接受护理,从而影响整体护理。

目的

本研究旨在确定艾滋病毒阳性人群中糖尿病和高血压的患病率。

地点

该研究在夸祖鲁-纳塔尔省德班南部的地区医院温特沃思医院进行。

方法

本横断面研究旨在确定在埃滕哈赫区的一家地区医院的 ART 诊所就诊的艾滋病毒阳性患者中两种 NCD(即糖尿病和高血压)的患病率。我们比较了有和没有合并症的患者的社会人口统计学和临床特征。对 301 名艾滋病毒阳性患者进行了结构化问卷调查。

结果

在 301 名患者中,230 名(76.41%)仅有 HIV(95%置信区间[CI]:71.25-80.89),71 名(23.59%)患有 HIV 和至少一种合并症,即糖尿病和/或高血压(95%CI:19.11-28.75)。高血压是最常见的合并症。本研究表明,ART 的持续时间与合并症之间没有关联。年龄较大和体重指数(BMI)与合并症有关,而性别和种族则没有关联。

结论

在该地区机构的 ARV 诊所就诊的艾滋病毒阳性患者中,糖尿病和高血压等非传染性疾病确实构成了负担。本研究强调了必须为 HIV 阳性患者因寿命延长和体重增加而导致的 NCD 负担增加做好规划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcb3/8517750/ad0b0047c7aa/PHCFM-13-2766-g001.jpg

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