Xue Siqi, Husain M Ishrat, Ortiz Abigail, Husain M Omair, Daskalakis Zafiris J, Mulsant Benoit H
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Centre for Addiction and Mental Health, Toronto, ON, Canada.
SAGE Open Med. 2020 Dec 14;8:2050312120981178. doi: 10.1177/2050312120981178. eCollection 2020.
The COVID-19 pandemic has posed significant challenges to health care globally, and individuals with bipolar disorder are likely disproportionally affected. Based on review of literature and collective clinical experience, we discuss that without special intervention, individuals with bipolar disorder will experience poorer physical and mental health outcomes due to interplay of patient, provider and societal factors. Some risk factors associated with bipolar disorder, including irregular social rhythms, risk-taking behaviours, substantial medical comorbidities, and prevalent substance use, may be compounded by lockdowns, social isolation and decrease in preventive and maintenance care. We further discuss implications for clinical research of bipolar disorders during the pandemic. Finally, we propose mitigation strategies on working with individuals with bipolar disorder in a clinical and research context, focusing on digital medicine strategies to improve quality of and accessibility to service.
新冠疫情给全球医疗保健带来了重大挑战,双相情感障碍患者可能受到的影响尤为严重。基于文献综述和集体临床经验,我们讨论了在没有特殊干预的情况下,由于患者、医疗服务提供者和社会因素的相互作用,双相情感障碍患者的身心健康状况将更差。一些与双相情感障碍相关的风险因素,包括不规律的社会节奏、冒险行为、大量的合并症以及普遍存在的物质使用问题,可能会因封锁、社会隔离以及预防和维持性治疗的减少而加剧。我们进一步讨论了疫情期间双相情感障碍临床研究的意义。最后,我们提出了在临床和研究背景下与双相情感障碍患者合作的缓解策略,重点是数字医学策略,以提高服务质量和可及性。