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COVID-19 及其他大流行和传染病对患有精神障碍既往史人群的影响:系统综述方案及临床照护建议。

Impact of COVID-19 and other pandemics and epidemics on people with pre-existing mental disorders: a systematic review protocol and suggestions for clinical care.

机构信息

Undergraduate Medical Education Program, Michael G. DeGroote School of Medicine, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada.

Department of Psychiatry and Behavioural Neurosciences, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada.

出版信息

BMJ Open. 2020 Sep 1;10(9):e040229. doi: 10.1136/bmjopen-2020-040229.

Abstract

INTRODUCTION

The current COVID-19 pandemic has resulted in high rates of infection and death, as well as widespread social disruption and a reduction in access to healthcare services and support. There is growing concern over how the pandemic, as well as measures put in place to curb the pandemic, will impact people with mental disorders. We aim to study the effect of pandemics and epidemics on mental health outcomes for people with premorbid mental disorders.

METHODS AND ANALYSIS

With our predefined search strategy, we will search five databases for studies reporting on mental health outcomes in people with pre-existing mental disorders during pandemic and epidemic settings. Search dates are planned as follows: 5 May 2020 and 23 July 2020. The following databases will be searched: MEDLINE/PubMed, CINAHL, PsycINFO, MedRxiv and EMBASE. Data will be screened and extracted in duplicate by two independent reviewers. Studies involving non-clinical populations or patients diagnosed with a mental disorder a pandemic/epidemic will be excluded. We will include data collected from all pandemics and epidemics throughout history, including the present COVID-19 pandemic. If possible, study findings will be combined in meta-analyses, and subgroup analyses will be performed. We hope that this review will shed light on the impact of pandemics and epidemics on those with pre-existing mental disorders. Knowledge generated may inform future intervention studies as well as healthcare policies. Given the potential implications of the current pandemic measures (ie, disruption of healthcare services) on mental health, we will also compile a list of existing mental health resources.

ETHICS AND DISSEMINATION

No ethical approval is required for this protocol and proposed systematic review as we will only use data from previously published papers that have themselves received ethics clearance and used proper informed consent procedures.

SYSTEMATIC REVIEW REGISTRATION

PROSPERO registration number: CRD42020179611.

摘要

简介

当前的 COVID-19 大流行导致了高感染率和死亡率,以及广泛的社会混乱以及医疗保健服务和支持的减少。人们越来越担心大流行以及为遏制大流行而采取的措施将如何影响患有精神障碍的人群。我们旨在研究大流行和流行病对有前驱精神障碍的人群的心理健康结果的影响。

方法和分析

我们将使用预先设定的搜索策略,在五个数据库中搜索报告大流行和流行期间有前驱精神障碍的人群的心理健康结果的研究。搜索日期计划如下:2020 年 5 月 5 日和 7 月 23 日。将搜索以下数据库:MEDLINE/PubMed、CINAHL、PsycINFO、MedRxiv 和 EMBASE。将由两名独立审查员重复筛选和提取数据。将排除涉及非临床人群或在大流行/流行期间被诊断出患有精神障碍的患者的研究。我们将包括从历史上所有大流行和流行病中收集的数据,包括当前的 COVID-19 大流行。如果可能,将对研究结果进行合并分析,并进行亚组分析。我们希望本综述将揭示大流行和流行病对有前驱精神障碍的人群的影响。产生的知识可能会为未来的干预研究以及医疗保健政策提供信息。鉴于当前大流行措施(即医疗保健服务中断)对心理健康的潜在影响,我们还将编制一份现有的心理健康资源清单。

伦理和传播

由于我们仅将使用先前已获得伦理批准并使用适当的知情同意程序的已发表论文中的数据,因此本方案和拟议的系统评价不需要伦理批准。

系统评价注册

PROSPERO 注册号:CRD42020179611。

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