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一名新冠肺炎患者出现类似川崎病的成人炎症性多系统综合征

Adult Inflammatory Multi-System Syndrome Mimicking Kawasaki Disease in a Patient With COVID-19.

作者信息

Malangu Boniface, Quintero Javier A, Capitle Eugenio M

机构信息

Internal Medicine, Rutgers New Jersey Medical School, Newark, USA.

Rheumatology, Rutgers New Jersey Medical School, Newark, USA.

出版信息

Cureus. 2020 Nov 28;12(11):e11750. doi: 10.7759/cureus.11750.

Abstract

We describe a 46-year-old male with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection who presented as a Kawasaki-like syndrome with features including prolonged fever, bilateral conjunctivitis, oral mucosal swelling, diffuse erythematous rash, cervical and hilar lymphadenopathy, as well as cardiovascular complications and multi-organ failure. There are several reports of a similar clinical entity mimicking Kawasaki disease (KD) in the pediatric population, which has been termed Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) by the Royal College of Pediatric and Child Health. To our knowledge, to date, there has been only one case report of COVID-19 presenting as KD in an adult patient.

摘要

我们描述了一名46岁男性,患有严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染,表现为川崎样综合征,其特征包括持续发热、双侧结膜炎、口腔黏膜肿胀、弥漫性红斑疹、颈部和肺门淋巴结病,以及心血管并发症和多器官功能衰竭。有几篇报道称,儿科人群中出现了类似川崎病(KD)的临床病症,英国皇家儿科和儿童健康学院将其称为与SARS-CoV-2暂时相关的儿童炎症性多系统综合征(PIMS-TS)。据我们所知,迄今为止,仅有一例关于成人患者COVID-19表现为KD的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ce1/7773524/4dbbc3cee858/cureus-0012-00000011750-i01.jpg

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