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增材制造与传统制造的近β型Ti-25Nb-3Zr-3Mo-2Sn合金的微观结构与生物腐蚀性能比较

Comparison of the Microstructure and Biocorrosion Properties of Additively Manufactured and Conventionally Fabricated near β Ti-25Nb-3Zr-3Mo-2Sn Alloy.

作者信息

Dargusch Matthew S, Wang Gui, Kent Damon, Bermingham Michael, Venezuela Jeffrey, Frith Jessica E, Yu Zhentao, Yu Sen, Shi Zhiming

机构信息

Queensland Centre for Advanced Materials Processing and Manufacturing (AMPAM), The University of Queensland, Brisbane 4072, Australia.

School of Science and Engineering, University of the Sunshine Coast, Sippy Downs, 4556, Queensland, Australia.

出版信息

ACS Biomater Sci Eng. 2019 Nov 11;5(11):5844-5856. doi: 10.1021/acsbiomaterials.9b00596. Epub 2019 Oct 21.

Abstract

The microstructure and biodegradability of a near β Ti-25Nb-3Zr-3Mo-2Sn alloy produced by laser engineered net shaping have been compared to those of alloys produced via casting and cold rolling in order to identify the key effects of processing pathways on the development of microstructure and biocorrosion properties. Results confirm the significant influence of processing technique on microstructure and concomitant biocompatibility of the alloy. Tests using mesenchymal stem cells confirm the ability of the additively manufactured alloy to support cell adhesion and spreading.

摘要

通过激光工程净成形制备的近β型Ti-25Nb-3Zr-3Mo-2Sn合金的微观结构和生物降解性,已与通过铸造和冷轧制备的合金进行了比较,以确定加工路径对微观结构发展和生物腐蚀性能的关键影响。结果证实了加工技术对合金微观结构和伴随生物相容性的显著影响。使用间充质干细胞进行的测试证实了增材制造合金支持细胞粘附和铺展的能力。

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