糖尿病视网膜病变中的氧化应激
Oxidative Stress in Diabetic Retinopathy.
作者信息
Ortega Ángel L
机构信息
Department of Physiology, Faculty of Pharmacy, University of Valencia, Vicente Andrés Estellés Av. s/n, 46100 Burjassot, Spain.
出版信息
Antioxidants (Basel). 2021 Jan 4;10(1):50. doi: 10.3390/antiox10010050.
Abstract
Diabetic Retinopathy (DR) is a progressive asymptomatic neuro-vascular complication of diabetes that triggers irreversible retinal damage [...].
摘要
糖尿病视网膜病变（DR）是一种糖尿病进展性无症状神经血管并发症，可引发不可逆的视网膜损伤[...]。
相似文献
1
Oxidative Stress in Diabetic Retinopathy.糖尿病视网膜病变中的氧化应激
Antioxidants (Basel). 2021 Jan 4;10(1):50. doi: 10.3390/antiox10010050.
2
Hypoxia and oxidative stress in the causation of diabetic retinopathy.糖尿病视网膜病变病因中的缺氧与氧化应激
Curr Diabetes Rev. 2011 Sep;7(5):291-304. doi: 10.2174/157339911797415620.
3
Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice.玻璃体内注射多能间充质基质细胞可在糖尿病小鼠视网膜中触发细胞保护微环境。
Stem Cell Res Ther. 2016 Mar 16;7:42. doi: 10.1186/s13287-016-0299-y.
4
Spermine oxidase: A promising therapeutic target for neurodegeneration in diabetic retinopathy.精脒氧化酶：糖尿病性视网膜病变神经退行性变的有前途的治疗靶点。
Pharmacol Res. 2019 Sep;147:104299. doi: 10.1016/j.phrs.2019.104299. Epub 2019 Jun 15.
5
Role of Oxidative Stress in Diabetic Retinopathy and the Beneficial Effects of Flavonoids.氧化应激在糖尿病视网膜病变中的作用及类黄酮的有益作用。
Curr Pharm Des. 2018;24(19):2180-2187. doi: 10.2174/1381612824666180515151043.
6
Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress.糖尿病视网膜病变的发病机制及褪黑素的改善作用；自噬、炎症和氧化应激的参与
Life Sci. 2018 Jan 15;193:20-33. doi: 10.1016/j.lfs.2017.12.001. Epub 2017 Dec 5.
7
The role of oxidative stress after retinal laser photocoagulation in nonproliferative diabetic retinopathy.视网膜激光光凝术后氧化应激在非增殖性糖尿病视网膜病变中的作用。
Coll Antropol. 2011 Sep;35(3):835-40.
8
Protective effects of methane-rich saline on diabetic retinopathy via anti-inflammation in a streptozotocin-induced diabetic rat model.富含甲烷的盐水通过抗炎症对链脲佐菌素诱导的糖尿病大鼠模型中的糖尿病视网膜病变产生保护作用。
Biochem Biophys Res Commun. 2015 Oct 16;466(2):155-61. doi: 10.1016/j.bbrc.2015.08.121. Epub 2015 Sep 9.
9
Mechanisms involved in the development of diabetic retinopathy induced by oxidative stress.氧化应激诱导糖尿病视网膜病变发生发展的相关机制。
Redox Rep. 2017 Jan;22(1):10-16. doi: 10.1080/13510002.2016.1205303. Epub 2016 Jul 15.
10
Crocin Inhibits Oxidative Stress and Pro-inflammatory Response of Microglial Cells Associated with Diabetic Retinopathy Through the Activation of PI3K/Akt Signaling Pathway.西红花苷通过激活PI3K/Akt信号通路抑制与糖尿病视网膜病变相关的小胶质细胞的氧化应激和促炎反应。
J Mol Neurosci. 2017 Apr;61(4):581-589. doi: 10.1007/s12031-017-0899-8. Epub 2017 Feb 25.
引用本文的文献
1
Enhancing Retinal Resilience: The Neuroprotective Promise of BDNF in Diabetic Retinopathy.增强视网膜韧性：脑源性神经营养因子在糖尿病视网膜病变中的神经保护前景。
Life (Basel). 2025 Feb 9;15(2):263. doi: 10.3390/life15020263.
2
Study on the mechanism of plant metabolites to intervene oxidative stress in diabetic retinopathy.植物代谢产物干预糖尿病视网膜病变氧化应激机制的研究
Front Pharmacol. 2025 Feb 5;16:1517964. doi: 10.3389/fphar.2025.1517964. eCollection 2025.
3
Identifying Therapeutic Targets and Potential Drugs for Diabetic Retinopathy: Focus on Oxidative Stress and Immune Infiltration.确定糖尿病视网膜病变的治疗靶点和潜在药物：聚焦于氧化应激和免疫浸润
J Inflamm Res. 2025 Feb 14;18:2205-2227. doi: 10.2147/JIR.S500214. eCollection 2025.
4
Clinical serum lipidomic profiling revealed potential lipid biomarkers for early diabetic retinopathy.临床血清脂质组学分析揭示了早期糖尿病视网膜病变的潜在脂质生物标志物。
Sci Rep. 2024 Jul 2;14(1):15148. doi: 10.1038/s41598-024-66157-z.
5
Effect of High-Sucrose Diet on the Occurrence and Progression of Diabetic Retinopathy and Dietary Modification Strategies.高糖饮食对糖尿病视网膜病变的发生和进展的影响及饮食调整策略。
Nutrients. 2024 May 5;16(9):1393. doi: 10.3390/nu16091393.
6
Antioxidant potential of chlorogenic acid in Age-Related eye diseases.绿原酸在年龄相关性眼病中的抗氧化潜力。
Pharmacol Res Perspect. 2024 Feb;12(1):e1162. doi: 10.1002/prp2.1162.
7
Role of Oxidative Stress in Retinal Disease and the Early Intervention Strategies: A Review.氧化应激在视网膜疾病中的作用及早期干预策略：综述。
Oxid Med Cell Longev. 2022 Oct 14;2022:7836828. doi: 10.1155/2022/7836828. eCollection 2022.
8
Long-Term Oral Administration of Salidroside Alleviates Diabetic Retinopathy in db/db Mice.长期口服红景天苷可减轻 db/db 小鼠的糖尿病视网膜病变。
Front Endocrinol (Lausanne). 2022 Mar 16;13:861452. doi: 10.3389/fendo.2022.861452. eCollection 2022.
9
Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene.提取物通过上调Nrf-2基因减轻糖尿病大鼠的氧化还原失衡和炎症。
Int J Inflam. 2021 Dec 16;2021:9778486. doi: 10.1155/2021/9778486. eCollection 2021.
10
In Vitro Bioactivity of Astaxanthin and Peptides from Hydrolisates of Shrimp () By-Products: From the Extraction Process to Biological Effect Evaluation, as Pilot Actions for the Strategy "From Waste to Profit".虾（）副产物水解产物中天冬氨酸虾青素和肽的体外生物活性：从提取过程到生物效应评价，作为“变废为宝”战略的初步行动。
Mar Drugs. 2021 Apr 13;19(4):216. doi: 10.3390/md19040216.
本文引用的文献
1
Glyoxalase System as a Therapeutic Target against Diabetic Retinopathy.乙二醛酶系统作为糖尿病视网膜病变的治疗靶点
Antioxidants (Basel). 2020 Oct 30;9(11):1062. doi: 10.3390/antiox9111062.
2
Diabetic Retinopathy: The Role of Mitochondria in the Neural Retina and Microvascular Disease.糖尿病视网膜病变：线粒体在神经视网膜和微血管疾病中的作用
Antioxidants (Basel). 2020 Sep 23;9(10):905. doi: 10.3390/antiox9100905.
3
Importance of the Use of Oxidative Stress Biomarkers and Inflammatory Profile in Aqueous and Vitreous Humor in Diabetic Retinopathy.氧化应激生物标志物及房水和玻璃体液中炎症指标在糖尿病视网膜病变中的应用重要性
Antioxidants (Basel). 2020 Sep 20;9(9):891. doi: 10.3390/antiox9090891.
4
Beneficial Effects of Glucagon-Like Peptide-1 (GLP-1) in Diabetes-Induced Retinal Abnormalities: Involvement of Oxidative Stress.胰高血糖素样肽-1（GLP-1）对糖尿病诱导的视网膜异常的有益作用：氧化应激的参与
Antioxidants (Basel). 2020 Sep 10;9(9):846. doi: 10.3390/antiox9090846.
5
Vitamin D Protects against Oxidative Stress and Inflammation in Human Retinal Cells.维生素D可保护人类视网膜细胞免受氧化应激和炎症的影响。
Antioxidants (Basel). 2020 Sep 8;9(9):838. doi: 10.3390/antiox9090838.
6
Antioxidative Effects of Ascorbic Acid and Astaxanthin on ARPE-19 Cells in an Oxidative Stress Model.抗坏血酸和虾青素在氧化应激模型中对ARPE-19细胞的抗氧化作用。
Antioxidants (Basel). 2020 Sep 6;9(9):833. doi: 10.3390/antiox9090833.
7
A Higher Proportion of Eicosapentaenoic Acid (EPA) When Combined with Docosahexaenoic Acid (DHA) in Omega-3 Dietary Supplements Provides Higher Antioxidant Effects in Human Retinal Cells.在ω-3膳食补充剂中，二十碳五烯酸（EPA）与二十二碳六烯酸（DHA）联合使用时比例更高，可在人类视网膜细胞中提供更高的抗氧化效果。
Antioxidants (Basel). 2020 Sep 4;9(9):828. doi: 10.3390/antiox9090828.
8
Astaxanthin Protects Retinal Photoreceptor Cells against High Glucose-Induced Oxidative Stress by Induction of Antioxidant Enzymes via the PI3K/Akt/Nrf2 Pathway.虾青素通过PI3K/Akt/Nrf2途径诱导抗氧化酶，保护视网膜光感受器细胞免受高糖诱导的氧化应激。
Antioxidants (Basel). 2020 Aug 10;9(8):729. doi: 10.3390/antiox9080729.
9
Protective Effect of Fenofibrate on Oxidative Stress-Induced Apoptosis in Retinal-Choroidal Vascular Endothelial Cells: Implication for Diabetic Retinopathy Treatment.非诺贝特对氧化应激诱导的视网膜-脉络膜血管内皮细胞凋亡的保护作用：对糖尿病视网膜病变治疗的意义。
Antioxidants (Basel). 2020 Aug 5;9(8):712. doi: 10.3390/antiox9080712.
10
Extracellular Vesicles and MicroRNA: Putative Role in Diagnosis and Treatment of Diabetic Retinopathy.细胞外囊泡与微小RNA：在糖尿病视网膜病变诊断和治疗中的潜在作用
Antioxidants (Basel). 2020 Aug 4;9(8):705. doi: 10.3390/antiox9080705.
Zotero 插件