Department of Neurology, Oregon Health & Science University School of Medicine, OR, USA.
Department of Occupational Therapy, Univeristy of Pittsburgh School of Health and Rehabilitation Sciences, PA, USA.
J Appl Gerontol. 2021 Nov;40(11):1579-1586. doi: 10.1177/0733464820984283. Epub 2021 Jan 6.
We examined features of everyday activities (capacity and frequency) between older adults with and without cognitive impairment over 12 months. Participants aged ≥60 years and at risk for depression were included (n = 260); 26% ( = 69) had an acquired cognitive impairment at baseline. Cognitive impairment was defined as one standard deviation below norms on the Repeatable Battery for the Assessment of Neuropsychological Status. Features of everyday activities were measured by a computerized adaptive test version of Late-Life Function and Disability Instrument (LLFDI) at six time points (baseline, 6 weeks, 3, 6, 9, 12 months). There were significant between-group differences in activity frequency ( = .04), but not activity capacity ( = .05). The group difference in activity frequency exceeded minimal detectable changes (MDC = 3.7) and reached moderate clinical meaningfulness (∆ at six time points = 3.7-4.7). Generalized linear mixed models revealed no Group × Time interactions on activity capacity and frequency ( = .65 and = .98). Practitioners may assess changes in activity frequency to monitor cognitive status of clients even when there is no loss of activity capacity.
我们在 12 个月的时间里,观察了认知障碍老年人和无认知障碍老年人的日常活动特征(活动量和频率)。参与者年龄≥60 岁且有抑郁风险(n=260);26%(=69)的人在基线时患有获得性认知障碍。认知障碍的定义是重复神经心理状态评估的可重复电池测试结果低于正常标准一个标准差。日常活动特征通过计算机自适应测试版本的老年功能和残疾仪器(LLFDI)在六个时间点(基线、6 周、3、6、9 和 12 个月)进行测量。在活动频率方面存在显著的组间差异(=0.04),但在活动量方面没有差异(=0.05)。活动频率的组间差异超过最小可检测变化(MDC=3.7),达到中度临床意义(在六个时间点的∆=3.7-4.7)。广义线性混合模型显示,在活动量和频率方面,组间没有交互作用(=0.65 和=0.98)。即使没有活动量的损失,从业者也可以评估活动频率的变化,以监测客户的认知状态。