Khan Inamullah, Quddusi Ayesha, Waqas Muhammad, Rai Hamid Hussain, Bakhshi Saqib Kamran, Shamim Muhammad Shahzad, Jooma Rashid
Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Department of Neuroscience, Centre for Neuroscience, Queens University, Kingston, Ontario, Canada.
Surg Neurol Int. 2020 Nov 11;11:379. doi: 10.25259/SNI_607_2019. eCollection 2020.
Decompressive craniectomy (DC) is the preferred surgical management option for lowering refractory intracranial pressure in cases of traumatic brain injury (TBI). A number of randomized controlled trials have demonstrated decreased mortality but increased morbidity following DC for TBI patients. Here, we reviewed the frequency of postoperative hemorrhagic complications following DC correlating with poor outcomes.
We retrospectively reviewed the medical records of patients who presented with TBI and underwent DC during the years 2015-2017. The frequency and characteristics of hemorrhagic complications were correlated with the patients' outcomes.
There were 74 patients with TBI included in the study who underwent DC. Of these, 31 patients developed expansion of existing hemorrhagic lesions, 13 had new contusions, three developed new extradural hemorrhages, two developed new subdural hematomas, and one patient developed an intraventricular hemorrhage. Those who developed expansion of existing hemorrhagic lesions following DC had longer ICU stays and poorer outcomes (Glasgow outcome scale).
After 74 DC performed in TBI patients, 67% developed new hemorrhagic lesions or expansion of previously existing hemorrhages. This finding negatively impacted clinical outcomes, including mortality.
去骨瓣减压术(DC)是创伤性脑损伤(TBI)患者降低难治性颅内压的首选手术治疗方法。多项随机对照试验表明,TBI患者接受DC治疗后死亡率降低,但发病率增加。在此,我们回顾了DC术后出血性并发症的发生频率及其与不良预后的相关性。
我们回顾性分析了2015年至2017年间因TBI接受DC治疗的患者的病历。出血性并发症的发生频率和特征与患者的预后相关。
本研究纳入74例接受DC治疗的TBI患者。其中,31例患者原有出血性病变扩大,13例出现新的挫伤,3例出现新的硬膜外出血,2例出现新的硬膜下血肿,1例患者出现脑室内出血。DC术后原有出血性病变扩大的患者入住重症监护病房(ICU)的时间更长,预后更差(格拉斯哥预后评分)。
74例TBI患者接受DC治疗后,67%出现新的出血性病变或原有出血扩大。这一发现对包括死亡率在内的临床结局产生了负面影响。