Ngoc Tran Thi Bich, Oanh Duong Thi, Pineda Lane, Ayudhya Suparlark, de Groot Nienke, Han Yanming
Department of Animal Feed and Nutrition, National Institute of Animal Science, Ha Noi, Vietnam.
Trouw Nutrition R&D, Amersfoort, The Netherlands.
Transl Anim Sci. 2020 Nov 27;4(4):txaa211. doi: 10.1093/tas/txaa211. eCollection 2020 Oct.
This study was carried out to evaluate the effect of Selacid Green Growth (GG) or antibiotic growth promoter (AGP) on the performance and economics of grow-finish (GF) pigs. The Selacid GG is a blend of short-chain fatty acids (formic acid, acetic acid, lactic acid, propionic acid, citric acid, and sorbic acid), buffered organic acid (ammonium formate), and a combination of medium-chain fatty acids (C8, C10, and C12). A total of 312 grower pigs (Yorkshire × Landrace × Duroc) with initial body weight (BW) of 26.5 ± 0.92 kg were used in a 90-d feeding trial. The pigs were allocated randomly to three treatments consisting of eight replicate pens with 13 pigs each. The treatments tested included a 1) negative control (control): basal diet without colistin and Selacid GG, 2) positive control (AGP): basal diet with colistin (20 g/ton), and 3) Feed additive (Selacid GG): basal diet with Selacid GG (2 kg/ton). The results showed that, over the entire period of the experiment, the dietary supplementation of Selacid GG elicited a similar effect as AGP on feed cost and on all growth parameters measured ( > 0.05). In relation to the control group, Selacid GG significantly improved the final BW (+3.4 kg or 3.6%), average daily gain (+39 g/pig or 5.3%), and gain:feed (+30 g or 8.1%) of pigs ( < 0.05). In addition, the feeding of Selacid GG reduced feed cost (-0.078 USD) per kilogram BW gain. The average daily feed intake was not affected by dietary treatments ( > 0.05). was prevalent in 46 out of 48 fecal samples tested. All isolates were resistant to colistin, amox-colistin, ciprofloxacin, and enrofloxacin. The number of isolates resistant to amoxicillin/clavulanic, cefotaxime, ceftiofur, and norfloxacin was significantly reduced, whereas the inhibitory zones of amocxillin/clavulanic acid were increased; and the susceptibility of to amoxcillin/clavulanic, cefotaxime, ceftiofur, ciprofloxacin, nofloxacin, and flumequin was increased when Selacid GG was added in the feeds ( < 0.05). The findings of the study suggest that Selacid GG is a cost-effective product with the same efficacy as AGP in promoting the growth and economic performance of GF pigs. The product is safe and can be added to the diet of GF pigs without developing resistance to selected antibiotics.
本研究旨在评估赛拉西绿生长剂（GG）或抗生素生长促进剂（AGP）对生长育肥（GF）猪生产性能和经济效益的影响。赛拉西GG是短链脂肪酸（甲酸、乙酸、乳酸、丙酸、柠檬酸和山梨酸）、缓冲有机酸（甲酸铵）以及中链脂肪酸（C8、C10和C12）的混合物。总共312头初始体重（BW）为26.5±0.92千克的生长猪（约克夏×长白×杜洛克）用于为期90天的饲养试验。这些猪被随机分配到三个处理组，每个处理组有八个重复栏，每个栏中有13头猪。测试的处理包括：1）阴性对照（对照组）：不添加黏菌素和赛拉西GG的基础日粮；2）阳性对照（AGP）：添加黏菌素（20克/吨）的基础日粮；3）饲料添加剂（赛拉西GG）：添加赛拉西GG（2千克/吨）的基础日粮。结果表明，在整个实验期间，日粮中添加赛拉西GG在饲料成本和所有测量的生长参数方面产生了与AGP相似的效果（P>0.05）。与对照组相比，赛拉西GG显著提高了猪的末重（增加3.4千克或3.6%）、平均日增重（每头猪增加39克或5.3%）和增重：饲料比（增加30克或8.1%）（P<0.05）。此外，饲喂赛拉西GG降低了每千克体重增重的饲料成本（-0.078美元）。平均日采食量不受日粮处理的影响（P>0.05）。在所检测的48份粪便样本中，46份中存在[未明确的某种菌]。所有[未明确的某种菌]分离株对黏菌素、阿莫西林-黏菌素、环丙沙星和恩诺沙星耐药。对阿莫西林/克拉维酸、头孢噻肟、头孢噻呋和诺氟沙星耐药的[未明确的某种菌]分离株数量显著减少，而阿莫西林/克拉维酸的抑菌圈增大；当在饲料中添加赛拉西GG时，[未明确的某种菌]对阿莫西林/克拉维酸、头孢噻肟、头孢噻呋、环丙沙星、诺氟沙星和氟甲喹的敏感性增加（P<0.05）。该研究结果表明，赛拉西GG是一种具有成本效益的产品，在促进生长育肥猪的生长和经济效益方面与AGP具有相同的功效。该产品安全，可以添加到生长育肥猪的日粮中，且不会对所选抗生素产生耐药性。
