Faculty of Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 6500047, Kobe, Japan.
Chem Commun (Camb). 2021 Jan 26;57(6):725-728. doi: 10.1039/d0cc06117d.
We developed a system to directly produce gold nanoparticles in cells by intracellular mineralization in lower concentration than conventional methods using a peptide consisting of a cell-penetrating sequence and a gold ion-binding sequence. Furthermore, we could control the uniquely shaped gold nanostructures that were produced by changing peptide structures.
我们开发了一种系统,通过细胞内矿化作用在比传统方法更低的浓度下直接在细胞内产生金纳米粒子,该系统使用由细胞穿透序列和金离子结合序列组成的肽。此外,我们可以通过改变肽结构来控制所产生的具有独特形状的金纳米结构。