Fish L H, Mariash C N
Department of Medicine, University of Minnesota, Minneapolis 55455.
Arch Intern Med. 1988 Mar;148(3):709-11.
A 30-year-old woman presented with infertility, hyperprolactinemia, and pituitary enlargement. Although relatively asymptomatic, she was found to have primary hypothyroidism. She became pregnant within a month following institution of levothyroxine replacement, and the pituitary enlargement resolved within one year. We discuss the relationship between hypothyroidism, hyperprolactinemia, and pituitary enlargement. This case emphasizes the need for thyroidal status evaluation in patients with presumptive prolactin-producing pituitary tumors before initiation of therapy for the hyperprolactinemia.
一名30岁女性因不孕、高催乳素血症和垂体增大前来就诊。尽管相对无症状，但她被发现患有原发性甲状腺功能减退症。在开始左甲状腺素替代治疗后的一个月内她怀孕了，垂体增大在一年内消退。我们讨论了甲状腺功能减退症、高催乳素血症和垂体增大之间的关系。该病例强调了在对疑似催乳素分泌性垂体瘤患者开始高催乳素血症治疗之前评估甲状腺状态的必要性。
