Meyrick Thomas R H, Ridley C M, McGibbon D H, Black M M
Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.
Br J Dermatol. 1988 Jan;118(1):41-6. doi: 10.1111/j.1365-2133.1988.tb01748.x.
A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more first degree relatives with an autoimmune-related disease, 42% had an autoantibody at a titre greater than 1:20, and 59.5% had one or more of these autoimmune-related phenomena. No statistically significant differences in the natural history of lichen sclerosus et atrophicus were demonstrated between those patients with autoimmune-related phenomena and those without.
一项针对350名经组织学确诊为硬化性苔藓萎缩性病变的女性的自身免疫相关现象研究表明，21.5%的患者患有一种或多种自身免疫相关疾病，21%的患者有一位或多位患有自身免疫相关疾病的一级亲属，42%的患者自身抗体滴度大于1:20，59.5%的患者出现一种或多种这些自身免疫相关现象。自身免疫相关现象患者与无自身免疫相关现象患者之间，硬化性苔藓萎缩性病变的自然病程未显示出统计学上的显著差异。
