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头颈癌患者细胞因子水平与长期症状发展之间的关联

Associations Between Cytokine Levels and Long-Term Symptom Development in Head and Neck Cancer Patients.

作者信息

Schultze Benjamin Stuart

机构信息

Oregon Health and Science University, Portland, Oregon.

出版信息

J Adv Pract Oncol. 2019 Nov-Dec;10(8):790-802. doi: 10.6004/jadpro.2019.10.8.3.

DOI:10.6004/jadpro.2019.10.8.3
PMID:33425464
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7668884/
Abstract

Cytokines have been associated with the development of cancer cachexia. Cytokine dysregulation is thought to cause cachexia and its associated symptoms by negatively affecting physiological homeostasis. Cytokines that have been associated with cachexia are thought to be associated with symptom development. Despite this increased association, there is mixed data regarding the development of symptoms, such as pain, anorexia, and lethargy. The purpose of this retrospective study was to examine the association of cytokine and C-reactive protein levels over time to determine if levels were associated with symptom development.

摘要

细胞因子与癌症恶病质的发展有关。细胞因子失调被认为通过对生理稳态产生负面影响而导致恶病质及其相关症状。与恶病质相关的细胞因子被认为与症状发展有关。尽管这种关联有所增加，但关于疼痛、厌食和嗜睡等症状发展的数据却存在分歧。这项回顾性研究的目的是检查细胞因子和C反应蛋白水平随时间的关联，以确定这些水平是否与症状发展相关。