Khuanekkaphan Monsicha, Noysang Chanai, Khobjai Warachate
Department of Health and Aesthetics, Thai Traditional Medicine College, Rajamangala University of Technology Thanyaburi, Pathum Thani, Thailand.
Department of Innovation of Health Products, Thai Traditional Medicine College, Rajamangala University of Technology Thanyaburi, Pathum Thani, Thailand.
J Adv Pharm Technol Res. 2020 Oct-Dec;11(4):174-178. doi: 10.4103/japtr.JAPTR_79_20. Epub 2020 Oct 10.
, , and have been used as medicinal plants in Thailand. They are sources of phytochemicals that applications for esthetic and healthcare. The aim of this research was to examine the phytochemical constituents and anti-aging potential of these plants. The phytochemical compounds were performed using gas chromatography-mass spectrometry. The anti-aging activities were evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azinobis (3-ethylbenzothiazoline-6-sunfonic acid) (ABTS), anti-collagenase, and anti-elastase assays. The main interest phytochemical compounds of ethanolic extracts of , , were ethanol, 2-(-Octadecenyloxy), γ-sitosterol and hexadecanoic acid, and ethyl ester, respectively. The DPPH half-maximal inhibitory concentration (IC) results of , were 0.32 ± 0.01, 0.34 ± 0.00, and 0.35 ± 0.01 mg/mL, respectively. The ABTS result of extract showed high inhibitory activity at IC of the extract was 0.62 ± 0.12 mg/mL. The percentage of collagenase inhibition of , , and at 1.0 mg/mL was 78.13 ± 4.42, 85.94 ± 2.21, and 90.63 ± 0.00, respectively. The extract had a high percentage of elastase inhibition. Consequently, these research results suggest that phytochemicals may also provide a range of esthetic and health benefits. The phytochemical constituent could be used as anti-aging active ingredient for cosmetic and pharmaceutical industrials.
在泰国，[植物名称1]、[植物名称2]和[植物名称3]一直被用作药用植物。它们是植物化学物质的来源，具有美容和保健应用。本研究的目的是研究这些植物的植物化学成分和抗衰老潜力。使用气相色谱 - 质谱法分析植物化学化合物。通过2,2 - 二苯基 - 1 - 苦基肼（DPPH）、2,2'-偶氮二（3 - 乙基苯并噻唑啉 - 6 - 磺酸）（ABTS）、抗胶原酶和抗弹性蛋白酶测定来评估抗衰老活性。[植物名称1]、[植物名称2]和[植物名称3]乙醇提取物的主要植物化学化合物分别为乙醇、2 - （-十八烯氧基）、γ - 谷甾醇和十六烷酸以及乙酯。[植物名称1]、[植物名称2]和[植物名称3]的DPPH半数最大抑制浓度（IC）结果分别为0.32±0.01、0.34±0.00和0.35±0.01mg/mL。[植物名称2]提取物的ABTS结果显示在提取物IC为0.62±0.12mg/mL时具有高抑制活性。[植物名称1]、[植物名称2]和[植物名称3]在1.0mg/mL时的胶原酶抑制百分比分别为78.13±4.42、85.94±2.21和90.63±0.00。[植物名称3]提取物具有高百分比的弹性蛋白酶抑制作用。因此，这些研究结果表明植物化学物质也可能提供一系列美容和健康益处。植物化学成分可作为化妆品和制药工业的抗衰老活性成分。
