Centre technique d'appui et de formation (CETAF), Saint-Etienne, France.
Laboratory SNA-EPIS EA 4607, University Jean Monnet, Saint-Etienne, France.
Front Public Health. 2020 Dec 9;8:602238. doi: 10.3389/fpubh.2020.602238. eCollection 2020.
Previous cohorts studied the association of various types of physical activities with the incidence of cognitive disorders. The objective of this work was to analyze the association of leisure, domestic and professional physical activities with mild and moderate cognitive disorders in older people living in the community. We used retrospective data from the "FRéLE" (FRagilité: étude Longitudinale de ses Expressions) a longitudinal and observational study. Data collected included socio-demographic variables, lifestyle and health status. Cognitive disorders were assessed using the Montreal Cognitive Assessment (MoCA). Two cut-offs of MoCA were used to analyze mild and moderate cognitive disorders. Physical activity was assessed by the Physical Activity Scale for the Elderly (PASE) structured in three sections: leisure, household, and professional activities. Spline and logistic regression models were used to estimate the risk of cognitive disorders. At baseline, 428 participants (for study of mild disorders) and 1,271 participants (for study of moderate disorders) without cognitive disorders were included in the analysis. The mean ages were 74 and 78 years, respectively. After a 2-year follow-up, we found mild cognitive disorders in 154 participants (36%) and 71 cases of moderate cognitive disorders (5.6%). In multi-adjusted logistic models, domestic activities were associated with cognitive disorders, but not leisure and professional activities. We found an inverse relation between domestic sub-score and cognitive disorders defined by MoCA < 18. With a specific questionnaire and quantitative information on the type of activities, this study contributed to the debate on the beneficial effects of physical activity on cognition.
先前的研究队列已经探讨了各种类型的身体活动与认知障碍发病风险之间的关联。本研究旨在分析社区老年人的休闲、家务和职业身体活动与轻度和中度认知障碍之间的关联。我们使用了“FRéLE”（FRagilité: étude Longitudinale de ses Expressions）的回顾性数据，这是一项纵向观察性研究。收集的数据包括社会人口统计学变量、生活方式和健康状况。认知障碍使用蒙特利尔认知评估（MoCA）进行评估。我们使用 MoCA 的两个截断值来分析轻度和中度认知障碍。身体活动通过体力活动量表（PASE）进行评估，分为休闲、家务和职业活动三个部分。使用样条和逻辑回归模型来估计认知障碍的风险。在基线时，428 名参与者（用于研究轻度障碍）和 1271 名参与者（用于研究中度障碍）没有认知障碍纳入分析。平均年龄分别为 74 岁和 78 岁。经过 2 年的随访，我们发现 154 名参与者（36%）出现轻度认知障碍，71 名参与者（5.6%）出现中度认知障碍。在多因素调整的逻辑回归模型中，家务活动与认知障碍相关，但休闲和职业活动与认知障碍无关。我们发现家务活动亚量表与 MoCA<18 定义的认知障碍呈负相关。通过特定的问卷和关于活动类型的定量信息，本研究为身体活动对认知的有益影响的争论做出了贡献。
