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急性区域性隐匿性外层视网膜病变综合征:关于脉络膜、光感受器和视网膜功能的经验教训。

Acute zonal occult outer retinopathy complex disease: Lessons learned about choroid, photoreceptors, and retinal function.

作者信息

Pellegrini Francesco, Cirone Daniele, De Simone Luca, Marullo Michele, Cimino Luca

机构信息

Department of Ophthalmology, "Ospedale Santo Spirito," AUSL Pescara, Pescara, Italy.

Uveitis Service, Department of Ophthalmology, Villa Anna Hospital, San Benedetto del Tronto, Italy.

出版信息

Eur J Ophthalmol. 2021 Mar;31(2):817-822. doi: 10.1177/1120672120986376. Epub 2021 Jan 9.

DOI:10.1177/1120672120986376
PMID:33426906
Abstract

PURPOSE

Retinal photoreceptors layer integrity is considered essential to visual function. We report a case of acute zonal occult outer retinopathy (AZOOR) complex disease (namely AIBSE: acute idiopathic blind spot enlargement) in which apparently a full anatomic regeneration is not needed for a complete functional recovery.

METHODS

Case report with multimodal imaging.

REPORTS

Visual field recovery in the presence of photoreceptors layer disruption studied by means of Optical Coherence Tomography. Choroid and photoreceptors layer thickness thinned progressively during recovery.

CONCLUSION

This case suggests that anatomical retinal integrity as shown by OCT does not always correspond to visual function. Our case highlights that a complete visual recovery can occur even when structural abnormalities are still observable.

摘要

目的

视网膜光感受器层的完整性被认为对视觉功能至关重要。我们报告了一例急性区域性隐匿性外层视网膜病变(AZOOR)复杂疾病(即AIBSE:急性特发性盲点扩大),在该病例中,完全的功能恢复显然并不需要完全的解剖学再生。

方法

采用多模态成像的病例报告。

报告

通过光学相干断层扫描研究了在光感受器层破坏情况下的视野恢复情况。在恢复过程中,脉络膜和光感受器层厚度逐渐变薄。

结论

该病例表明,光学相干断层扫描显示的视网膜解剖学完整性并不总是与视觉功能相对应。我们的病例强调,即使结构异常仍然可以观察到,也可能出现完全的视觉恢复。

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Am J Ophthalmol Case Rep. 2024 Nov 29;36:102222. doi: 10.1016/j.ajoc.2024.102222. eCollection 2024 Dec.
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A systematic review of acute zonal occult outer retinopathy with a focus on attempted treatment modalities.急性区域性隐匿性外层视网膜病变的系统评价,重点关注尝试的治疗方式。
Curr Ophthalmol Rep. 2022 Dec;10(4):168-178. doi: 10.1007/s40135-022-00305-4. Epub 2022 Dec 1.
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Coarsening of choriocapillaris on optical coherence tomography angiography as a sign of acute idiopathic blind spot enlargement.
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Am J Ophthalmol Case Rep. 2022 May 2;26:101558. doi: 10.1016/j.ajoc.2022.101558. eCollection 2022 Jun.