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人类角膜:对缺氧环境的个体反应。

Human cornea: individual responses to hypoxic environments.

作者信息

Benjamin W J, Hill R M

机构信息

Ohio State University, College of Optometry, Columbus 43210-1240.

出版信息

Graefes Arch Clin Exp Ophthalmol. 1988;226(1):45-8. doi: 10.1007/BF02172717.

DOI:10.1007/BF02172717
PMID:3342975
Abstract

Using a micropolarographic system, the responses of seven human corneas to oxygen atmospheres ranging from 20.9% to 0% were measured. Under normal atmospheric conditions, ratios of oxygen demand were observed between corneas as great as 1.23:1. Following 0% oxygen conditions, however, these ratios rose to a maximum of 1.93:1, i.e., representing demand differences between particular corneas of nearly 2:1. Such differences may prove increasingly important in the gauging of patient suitability and safety in relation to hypoxic stress, e.g., the extended wear of contact lenses.

摘要

使用微极谱系统,测量了七个人类角膜对从20.9%到0%的氧气环境的反应。在正常大气条件下,观察到角膜之间的需氧比高达1.23:1。然而,在0%氧气条件下,这些比例上升到最大值1.93:1,即特定角膜之间的需求差异接近2:1。在衡量患者对缺氧应激(如隐形眼镜的长期佩戴)的适用性和安全性方面,这种差异可能会变得越来越重要。

相似文献

1
Human cornea: individual responses to hypoxic environments.人类角膜:对缺氧环境的个体反应。
Graefes Arch Clin Exp Ophthalmol. 1988;226(1):45-8. doi: 10.1007/BF02172717.
2
Human cornea: superior and central oxygen demands.人角膜:上方和中央的氧气需求。
Graefes Arch Clin Exp Ophthalmol. 1988;226(1):41-4. doi: 10.1007/BF02172716.
3
Closed-lid factors influencing human corneal oxygen demand.影响人角膜需氧量的闭眼因素。
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4
Human corneal oxygen demand: the closed-eye interval.人类角膜需氧量:闭眼间隔期
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Human cornea: oxygen uptake immediately following graded deprivation.人角膜:分级剥夺后即刻的氧摄取
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Determination of oxygen tension on rabbit corneas under contact lenses.隐形眼镜下兔角膜氧张力的测定。
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Oxygen demands with hybrid contact lenses.混合式隐形眼镜的氧气需求。
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引用本文的文献

1
Corneal oxygenation: blink frequency as a variable in rigid contact lens wear.角膜氧合作用:眨眼频率作为硬性隐形眼镜佩戴中的一个变量。
Br J Ophthalmol. 1990 Mar;74(3):168-71. doi: 10.1136/bjo.74.3.168.
2
Responses to oxygen deprivation: variations among human corneas.
Graefes Arch Clin Exp Ophthalmol. 1991;229(3):287-90. doi: 10.1007/BF00167886.

本文引用的文献

1
OXYGEN DEPRIVATION OF THE CORNEA BY CONTACT LENSES AND LID CLOSURE.
Am J Optom Arch Am Acad Optom. 1964 Nov;41:678-87. doi: 10.1097/00006324-196411000-00006.
2
OXYGEN DEPLETION OF A LIMITED RESERVOIR BY HUMAN CONJUNCTIVA.人类结膜对有限储库中氧气的消耗
Nature. 1963 Dec 7;200:1011-2. doi: 10.1038/2001011b0.
3
Apparent human corneal oxygen uptake rate.人角膜表观氧摄取率。
Am J Optom Physiol Opt. 1981 Oct;58(10):803-5. doi: 10.1097/00006324-198110000-00004.
4
Corneal swelling response to contact lenses worn under extended wear conditions.长时间佩戴隐形眼镜下的角膜肿胀反应。
Invest Ophthalmol Vis Sci. 1983 Feb;24(2):218-26.
5
The minimum precorneal oxygen tension to avoid corneal edema.避免角膜水肿的最低角膜前氧张力。
Invest Ophthalmol Vis Sci. 1984 Apr;25(4):476-80.
6
Polarography: an oxygen survey correlating oxygen transmissibility to "EOP" values.极谱法:一项将氧透过率与“等效渗透系数(EOP)”值相关联的氧含量调查。
Invest Ophthalmol Vis Sci. 1984 Dec;25(12):1451-3.
7
Equivalent oxygen percentage (EOP) technique: a standard calibration curve.等效氧百分比(EOP)技术:一条标准校准曲线。
Am J Optom Physiol Opt. 1984 Sep;61(9):601-4. doi: 10.1097/00006324-198409000-00011.
8
Human cornea: oxygen uptake immediately following graded deprivation.人角膜:分级剥夺后即刻的氧摄取
Graefes Arch Clin Exp Ophthalmol. 1985;223(1):47-9. doi: 10.1007/BF02150573.
9
Corneal endothelial polymegathism induced by PMMA contact lens wear.佩戴聚甲基丙烯酸甲酯隐形眼镜引起的角膜内皮细胞大小不均一性
Invest Ophthalmol Vis Sci. 1985 Jun;26(6):857-63.
10
Oxygen levels beneath the closed eyelid.闭合眼睑下的氧含量。
Invest Ophthalmol Vis Sci. 1979 Jan;18(1):93-5.