Benjamin W J, Hill R M
Graefes Arch Clin Exp Ophthalmol. 1986;224(3):291-4. doi: 10.1007/BF02143073.
A micropolarographic system was used to measure the flux of oxygen crossing the tear epithelial interface of the human cornea just following lid-closure periods of 0-15 min, and just following a series of brief lid openings (0.2-0.3 s) of frequencies from 0 to 30 times/min. In all, 462 measurements spanning those two formats were made on the corneas of seven young healthy subjects. In the extended-closure format the average rate increased over the first 5 min, then stabilized at 2.51 times the oxygen-uptake rate under normal open-eye conditions. In the brief lid-opening format, frequencies of 30 openings/min reduced the oxygen uptake rate to 70% of that of the stabilized closed eye. Individual differences noted among subjects may influence their relative success in extended contact lens wear, and natural lid and eye movements during sleep may have at least transient effects on corneal oxygen supply and demand during those periods.
使用微极谱系统测量在闭眼0至15分钟后以及一系列频率为0至30次/分钟的短暂睁眼（0.2至0.3秒）后，穿过人眼角膜泪液上皮界面的氧气通量。总共对7名年轻健康受试者的角膜进行了462次涵盖这两种形式的测量。在长时间闭眼形式中，平均速率在前5分钟内增加，然后稳定在正常睁眼条件下氧气摄取速率的2.51倍。在短暂睁眼形式中，30次/分钟的频率将氧气摄取速率降低至稳定闭眼时的70%。受试者之间观察到的个体差异可能会影响他们在长时间佩戴隐形眼镜方面的相对成功率，并且睡眠期间自然的眼睑和眼球运动在这些时间段内可能至少会对角膜的氧气供应和需求产生短暂影响。
