Lewis H, Sloan S H, Foos R Y
Jules Stein Eye Institute, UCLA School of Medicine.
Graefes Arch Clin Exp Ophthalmol. 1988;226(1):59-64. doi: 10.1007/BF02172720.
The clinicopathologic correlation of three eyes with massive intraocular hemorrhage in patients receiving anticoagulant therapy is reported. All three patients were apparently predisposed because of antecedent disciform macular degeneration. The hemorrhage arose from the extrachoroidal neovascular vessels within the disciform lesions and caused rupture of the retinal pigment epithelium with massive intraocular hemorrhage. Because of the risk of vision-threatening intraocular hemorrhage, patients with exudative macular degeneration requiring anticoagulant therapy should be managed by both ophthalmologists and internists.
本文报告了3例接受抗凝治疗的患者发生大量眼内出血的临床病理相关性。所有3例患者显然都因先前存在的盘状黄斑变性而具有易患因素。出血源自盘状病变内的脉络膜外新生血管，导致视网膜色素上皮破裂并发生大量眼内出血。由于存在威胁视力的眼内出血风险，需要抗凝治疗的渗出性黄斑变性患者应由眼科医生和内科医生共同管理。
