Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
China Institute of Veterinary Drug Control, Beijing 100081, China.
Viruses. 2021 Jan 7;13(1):73. doi: 10.3390/v13010073.
Nodaviruses are small bisegmented RNA viruses belonging to the family . Nodaviruses have been identified in different hosts, including insects, fishes, shrimps, prawns, dogs, and bats. A novel porcine nodavirus was first identified in the United States by applying next-generation sequencing on brain tissues of pigs with neurological signs, including uncontrollable shaking. RNA1 of the porcine nodavirus had the highest nucleotide identity (51.1%) to the Flock House virus, whereas its RNA2 shared the highest nucleotide identity (48%) with the RNA2 segment of caninovirus (Canine nodavirus). Genetic characterization classified porcine nodavirus as a new species under the genus . Further studies are needed to understand the pathogenicity and clinical impacts of this virus.
诺达病毒是属于 的小双节段 RNA 病毒。已在包括昆虫、鱼类、虾、对虾、狗和蝙蝠在内的不同宿主中鉴定出诺达病毒。一种新型猪诺达病毒最初是通过对具有神经症状（包括无法控制的颤抖）的猪的脑组织进行下一代测序在美国鉴定出来的。猪诺达病毒的 RNA1 与 Flock House 病毒具有最高的核苷酸同一性（51.1%），而其 RNA2 与犬诺达病毒（Canine nodavirus）的 RNA2 片段具有最高的核苷酸同一性（48%）。遗传特征将猪诺达病毒归类为 属中的一个新种。需要进一步的研究来了解该病毒的致病性和临床影响。
