Solís-García Gonzalo, Gutiérrez-Vélez Ana, Pescador Chamorro Isabel, Zamora-Flores Elena, Vigil-Vázquez Sara, Rodríguez-Corrales Elena, Sánchez-Luna Manuel
Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
An Pediatr (Engl Ed). 2021 Mar;94(3):173-178. doi: 10.1016/j.anpedi.2020.12.004. Epub 2020 Dec 19.
The impact of maternal SARS-CoV-2 infection and its risk of vertical transmission is still not well known. Recommendations from scientific societies seek to provide safety for newborns without compromising the benefits of early contact. The aim of the study is to describe characteristics and evolution of newborns born to mothers with SARS-CoV-2 infection, as well as the implemented measures following recommendations from the Sociedad Española de Neonatología.
Observational, prospective and single-center cohort study. A specific circuit was designed for mothers with SARS-CoV-2 infection and their newborns. Epidemiological and clinical data were collected. PCR were performed in newborns at delivery and at 14 days of age.
73 mothers and 75 newborns were included in the study. 95.9% of maternal infections were diagnosed during the third trimester of pregnancy, 43.8% were asymptomatic. Median gestational age was 38 weeks (IQR: 37-40), 25.9% of newborns required admission to Neonatology. Skin-to-skin mother care was performed in 68% of newborns, 80% received exclusive maternal or donated breast milk during hospital stay. No positive PCR results were observed in newborns at delivery, one case of positive PCR was observed in an asymptomatic neonate at 14 days of age.
Risk of SARS-CoV-2 transmission is low when complying to the recommendations issued by Sociedad Española de Neonatología, allowing rooming-in and promoting breastfeeding.
孕产妇感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的影响及其垂直传播风险仍未完全明确。科学协会的建议旨在为新生儿提供安全保障，同时不影响早期接触的益处。本研究的目的是描述SARS-CoV-2感染母亲所生新生儿的特征和病情发展，以及按照西班牙新生儿学会的建议所采取的措施。
观察性、前瞻性单中心队列研究。为SARS-CoV-2感染母亲及其新生儿设计了特定流程。收集流行病学和临床数据。在新生儿出生时及出生后14天进行聚合酶链反应（PCR）检测。
73名母亲和75名新生儿纳入研究。95.9%的孕产妇感染在妊娠晚期被诊断出，43.8%无症状。中位孕周为38周（四分位间距：37 - 40周），25.9%的新生儿需要入住新生儿科。68%的新生儿接受了母婴皮肤接触护理，80%在住院期间接受了纯母乳或捐赠母乳。新生儿出生时PCR检测均为阴性，1例无症状新生儿在14天时PCR检测呈阳性。
遵循西班牙新生儿学会发布的建议时，SARS-CoV-2传播风险较低，这使得母婴能够同室护理并促进母乳喂养。
