Alvarez de Saldaña S, de Ramírez A F, Ramírez Mata M
Rev Gastroenterol Mex. 1978 Sep-Dec;43(3):127-30.
Five different antacids were compared "in vitro" through titration with NaOH 0.5 N to observe their neutralising power towards HCl 1.0 N. Eight pH measurements were done for each antacid. The neutralising capacity of the antacid was calculated with a specific formula for each pH measure reading, with this information statistical calculation were made to compare the antacids among themselves, with suggest that the method can be useful in the valuation of newly produced antacid before their clinical application.
通过用0.5N的NaOH进行滴定，在“体外”比较了五种不同的抗酸剂，以观察它们对1.0N HCl的中和能力。每种抗酸剂进行了八次pH测量。根据每个pH测量读数的特定公式计算抗酸剂的中和能力，并利用这些信息进行统计计算以比较抗酸剂之间的差异，这表明该方法在新生产的抗酸剂临床应用前的评估中可能有用。
