Lei Geraldine Yanlei, Tay Kon Voi, Hern Qi Chong Cheryl, Ho Thomas
General Surgery Department, Tan Tock Seng Hospital, Singapore.
General Surgery Department, Tan Tock Seng Hospital, Singapore; General Surgery Department, Woodlands Health Campus, Singapore.
Int J Surg Case Rep. 2021 Feb;79:67-69. doi: 10.1016/j.ijscr.2020.11.085. Epub 2020 Dec 29.
Penile gangrene is a rare but fatal complication of calciphylaxis in end-stage renal disease (ESRD). To date, there are no guidelines on its management, and outcomes are generally poor with high mortality rate. We present a case of a diabetic patient with ESRD presenting with dry gangrene of the glans penis due to calciphylaxis and successfully treated with intravenous sodium thiosulfate (STS) and early total parathyroidectomy. We further analysed existing literatures on cases that utilized STS in the treatment of penile calciphylaxis.
阴茎坏疽是终末期肾病（ESRD）中钙过敏症罕见但致命的并发症。迄今为止，尚无关于其治疗的指南，且总体预后较差，死亡率较高。我们报告一例患有ESRD的糖尿病患者，因钙过敏症出现阴茎头干性坏疽，并通过静脉注射硫代硫酸钠（STS）和早期甲状旁腺全切术成功治愈。我们进一步分析了利用STS治疗阴茎钙过敏症的现有病例文献。
