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15 分钟咨询:如何识别和治疗急性肾损伤患儿。

Fifteen-minute consultation: how to identify and treat children with acute kidney injury.

机构信息

Department of Paediatric Nephrology, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland

Department of Paediatric Nephrology, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland.

出版信息

Arch Dis Child Educ Pract Ed. 2022 Feb;107(1):9-14. doi: 10.1136/archdischild-2020-319928. Epub 2021 Jan 12.

Abstract

Acute kidney injury (AKI) is under-recognised in children and neonates. It is associated with increased mortality and morbidity along with an increased incidence of chronic kidney disease in adulthood. It is important that paediatricians are able to recognise AKI quickly, enabling prompt treatment of reversible causes. In this article, we demonstrate an approach to recognising paediatric AKI, cessation of nephrotoxic medication, appropriate investigations and the importance of accurately assessing fluid status. The mainstay of treatment is attempting to mimic the kidneys ability to provide electrolyte and fluid homeostasis; this requires close observation and careful fluid management. We discuss referral to paediatric nephrology and the importance of long-term follow-up. We present an approach to AKI through case-presentation.

摘要

急性肾损伤(AKI)在儿童和新生儿中未得到充分认识。它与死亡率和发病率增加以及成年后慢性肾脏病的发病率增加有关。儿科医生能够快速识别 AKI 非常重要,以便及时治疗可逆病因。在本文中,我们展示了一种识别儿科 AKI 的方法,包括停止使用肾毒性药物、进行适当的检查以及准确评估液体状态的重要性。治疗的主要方法是试图模仿肾脏提供电解质和液体平衡的能力;这需要密切观察和仔细的液体管理。我们讨论了向儿科肾脏病学转诊的问题以及长期随访的重要性。我们通过病例介绍来介绍 AKI 的处理方法。

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