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超声评估下腔静脉在预防疝气和鞘膜积液手术中脊髓麻醉引起的低血压中的作用——一项前瞻性随机对照研究。

Role of ultrasonographic inferior venacaval assessment in averting spinal anaesthesia-induced hypotension for hernia and hydrocele surgeries-A prospective randomised controlled study.

作者信息

Ayyanagouda Basavaraja, Ajay B C, Joshi Chhaya, Hulakund S Y, Ganeshnavar Anilkumar, Archana E

机构信息

Department of Anaesthesiology, S N Medical College and HSK Hospital, Navanagar, Bagalkot, Karnataka, India.

出版信息

Indian J Anaesth. 2020 Oct;64(10):849-854. doi: 10.4103/ija.IJA_244_20. Epub 2020 Oct 1.

Abstract

BACKGROUND AND AIMS

Hypotension is one of the most common side effects of spinal anaesthesia and preoperative volume status is one of the predictive variables for developing spinal-induced hypotension (SIH). Inferior venacaval ultrasound (IVCUS) is effective to assess fluid responsiveness in critical care patients. The aim of this study was to evaluate the IVCUS-guided volume optimisation prior to spinal anaesthesia to prevent SIH and requirement of vasopressors.

METHODS

Eighty patients undergoing inguinal hernia/hydrocele surgeries under spinal anaesthesia were randomised into group A consisting of an IVCUS-guided volume optimisation before spinal anaesthesia and group B with no IVCUS assessment. Unpaired t-test and Z test were used for statistical analysis. Pearson's correlation coefficient was used to find correlation. The primary outcome was relative risk reduction in the incidence of SIH between the groups. Secondary outcomes were the need for vasopressor drugs, the total volume of fluids required throughout procedure, and correlation between IVC collapsibility index (IVCCI) versus prespinal fluids, IVCCI versus baseline mean arterial pressure (MAP).

RESULTS

The relative risk reduction in the incidence of SIH was lower in group A compared to group B which was 40% ( = 0.002 CI = 95%). The SIH in group A was 20% and group B was 50%. There was decreased requirement of vasopressors in group A compared to group B. Total IV fluids given was more in group A. There was a positive correlation between IVCCI and pre-spinal fluids.

CONCLUSION

IVCUS assessment reduces the SIH as well as requirement of vasopressor for hernia and hydrocele surgeries.

摘要

背景与目的

低血压是脊髓麻醉最常见的副作用之一,术前容量状态是发生脊髓诱导性低血压(SIH)的预测变量之一。下腔静脉超声(IVCUS)可有效评估重症患者的液体反应性。本研究的目的是评估脊髓麻醉前IVCUS引导下的容量优化,以预防SIH和血管升压药的使用需求。

方法

80例接受脊髓麻醉下腹股沟疝/鞘膜积液手术的患者被随机分为A组,在脊髓麻醉前进行IVCUS引导下的容量优化;B组不进行IVCUS评估。采用非配对t检验和Z检验进行统计分析。使用Pearson相关系数来寻找相关性。主要结局是两组间SIH发生率的相对风险降低。次要结局是血管升压药的使用需求、整个手术过程中所需的液体总量,以及下腔静脉塌陷指数(IVCCI)与脊髓前液体量、IVCCI与基线平均动脉压(MAP)之间的相关性。

结果

与B组相比,A组SIH发生率的相对风险降低率较低,为40%(P = 0.002,95%CI)。A组的SIH发生率为20%,B组为50%。与B组相比,A组血管升压药的使用需求减少。A组给予的静脉输液总量更多。IVCCI与脊髓前液体量之间存在正相关。

结论

IVCUS评估可降低腹股沟疝和鞘膜积液手术中SIH的发生率以及血管升压药的使用需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52a9/7791418/4a5cb49af8a7/IJA-64-849-g001.jpg

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