Ramadan Wafaa Mohammad, Hassan Arwa Mohammad, Ismail Mayada A, El Attar Yasmina Ahmed
Department of Dermatology and Venereology, Tanta University, Tanta, Egypt.
Department of Dermatology and Venereology, Faculty of Medicine, Tanta University, Tanta, Egypt.
J Cosmet Dermatol. 2021 May;20(5):1427-1434. doi: 10.1111/jocd.13935. Epub 2021 Jan 12.
Androgenetic alopecia (AGA) is a common hair loss disorder.
To evaluate the therapeutic effects of platelet-rich plasma (PRP) in androgenetic alopecia.
This study was done on 126 AGA patients, 42 patients survived as control group who received medical treatment, only other 84 patients were subdivided into two groups, and they received PRP sessions as co-adjuvant therapy using different methods administration. Patients were evaluated clinically, by dermoscopy and by digital dermoscopy to measure hair density and diameters before and after treatment.
PRP-treated patients showed statistically significant increase in hair density and diameter measurements than control group. These results increased by using microneedling as a method of PRP administration.
In AGA, the addition of "PRP with microneedling" to the combined medical treatment increases its efficacy and shortens the time needed for optimum improvement.
Single-blinded randomized controlled study.
雄激素性脱发（AGA）是一种常见的脱发疾病。
评估富血小板血浆（PRP）治疗雄激素性脱发的疗效。
本研究纳入126例AGA患者，42例患者作为对照组仅接受药物治疗，另外84例患者分为两组，采用不同给药方法接受PRP治疗作为辅助治疗。通过临床评估、皮肤镜检查和数字皮肤镜检查，测量患者治疗前后的头发密度和直径。
与对照组相比，接受PRP治疗的患者头发密度和直径测量值有统计学意义的增加。通过微针注射法给予PRP，这些结果有所提高。
在AGA治疗中，联合药物治疗时添加“微针注射PRP”可提高疗效并缩短达到最佳改善所需的时间。
单盲随机对照研究。
