Robinson L R, Jantra P, MacLean I C
Department of Rehabilitation Medicine, Rehabilitation Institute of Chicago, IL.
Muscle Nerve. 1988 Feb;11(2):174-80. doi: 10.1002/mus.880110214.
The purpose of this study was to determine central motor conduction times between the motor cortex and the C8 spinal cord level (MC/C8), the motor cortex and S1 cord level (MC/S1), and C8 and S1 (C8/S1). We stimulated 29 normal subjects with a transcranial high voltage (300-500 V), short duration spike waveform (time constant 50 mu sec) and recorded over the hypothenar or calf muscles. F wave and M response latencies were used to estimate peripheral conduction time. The mean MC/C8 conduction time was 4.4 +/- 0.6 msec. Out of 26 subjects tested, 14 had discernable responses in the calf. The mean MC/S1 conduction time was 13.1 +/- 2.5 msec, and the mean estimated C8/S1 conduction time was 8.5 +/- 2.3 msec. This technique accurately measures conduction time from the motor cortex to the cervical anterior horn cells but is less reliable for monitoring conduction to the sacral cord. These values will facilitate future studies in patients with suspected lesions of the descending motor pathways.
本研究的目的是确定运动皮层与颈8脊髓节段（MC/C8）、运动皮层与骶1脊髓节段（MC/S1）以及颈8和骶1（C8/S1）之间的中枢运动传导时间。我们用经颅高压（300 - 500V）、短持续时间的尖峰波形（时间常数50微秒）刺激29名正常受试者，并在小鱼际肌或小腿肌肉上进行记录。F波和M反应潜伏期用于估计外周传导时间。MC/C8的平均传导时间为4.4±0.6毫秒。在接受测试的26名受试者中，14名在小腿有可识别的反应。MC/S1的平均传导时间为13.1±2.5毫秒，估计的C8/S1平均传导时间为8.5±2.3毫秒。该技术能准确测量从运动皮层到颈前角细胞的传导时间，但监测到骶髓的传导时可靠性较低。这些数值将有助于未来对疑似下行运动通路病变患者的研究。
