化学生物学在抗击 SARS-CoV-2 中的作用。

The role of chemical biology in the fight against SARS-CoV-2.

机构信息

Department of Biochemistry and Biophysics, Department of Cancer Biology and Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, 422 Curie Blvd., Philadelphia, PA 19104, U.S.A.

出版信息

Biochem J. 2021 Jan 15;478(1):157-177. doi: 10.1042/BCJ20200514.

DOI:10.1042/BCJ20200514

PMID:33439990

Abstract

Since late 2019, biomedical labs all over the world have been struggling to cope with the 'new normal' and to find ways in which they can contribute to the fight against COVID-19. In this unique situation where a biomedical issue dominates people's lives and the news cycle, chemical biology has a great deal to contribute. This review will describe the importance of science at the chemistry/biology interface to both understand and combat the SARS-CoV-2 pandemic.

摘要

自 2019 年末以来，世界各地的生物医学实验室一直在努力应对“新常态”，并寻找能够为抗击 COVID-19 做出贡献的方法。在这种生物医学问题主导人们生活和新闻周期的特殊情况下，化学生物学有很多可以贡献。这篇综述将描述化学/生物学界面的科学对于理解和对抗 SARS-CoV-2 大流行的重要性。