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机器人辅助在胰腺手术中的应用:连续101例首例病例的经验

Implementation of Robotic Assistance in Pancreatic Surgery: Experiences from the First 101 Consecutive Cases.

作者信息

Timmermann Lea, Biebl Matthias, Schmelzle Moritz, Bahra Marcus, Malinka Thomas, Pratschke Johann

机构信息

Department of Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, 10551 Berlin, Germany.

出版信息

J Clin Med. 2021 Jan 11;10(2):229. doi: 10.3390/jcm10020229.

Abstract

Robotic assisted minimally invasive surgery has been implemented to overcome typical limitations of conventional laparoscopy such as lack of angulation, especially during creation of biliary and pancreatic anastomoses. With this retrospective analysis, we provide our experience with the first 101 consecutive robotic pancreatic resection performed at our center. Distal pancreatectomies (RDP, N = 44), total pancreatectomies (RTP, N = 3) and pancreaticoduodenectomies (RPD, N = 54) were included. Malignancy was found in 45.5% (RDP), 66.7% (RTP) and 61% (RPD). Procedure times decreased from the first to the second half of the cohort for RDP (218 min vs. 128 min, = 0.02) and RPD (378 min vs. 271 min, < 0.001). Overall complication rate was 63%, 33% and 66% for RPD, RPT and RDP, respectively. Reintervention and reoperation rates were 41% and 17% (RPD), 33% and 0% (RTP) and 50% and 11.4% (RPD), respectively. The thirty-day mortality rate was 5.6% for RPD and nil for RTP and RDP. Overall complication rate remained stable throughout the study period. In this series, implementation of robotic pancreas surgery was safe and feasible. Final evaluation of the anastomoses through the median retrieval incision compensated for the lack of haptic feedback during reconstruction and allowed for secure minimally invasive resection and reconstruction.

摘要

机器人辅助微创手术已被应用,以克服传统腹腔镜手术的典型局限性,如角度受限,尤其是在进行胆管和胰腺吻合术时。通过这项回顾性分析,我们介绍了在我们中心连续进行的首例101例机器人胰腺切除术的经验。其中包括远端胰腺切除术(RDP,n = 44)、全胰腺切除术(RTP,n = 3)和胰十二指肠切除术(RPD,n = 54)。RDP中恶性肿瘤的发生率为45.5%,RTP为66.7%,RPD为61%。RDP组和RPD组的手术时间从队列的前半部分到后半部分有所减少(RDP:218分钟对128分钟,P = 0.02;RPD:378分钟对271分钟,P < 0.001)。RPD、RPT和RDP的总体并发症发生率分别为63%、33%和66%。RPD的再次干预和再次手术率分别为41%和17%,RTP为33%和0%,RPD为50%和11.4%。RPD的30天死亡率为5.6%,RTP和RDP为零。在整个研究期间,总体并发症发生率保持稳定。在本系列研究中,机器人胰腺手术的实施是安全可行的。通过正中切口进行吻合口的最终评估弥补了重建过程中触觉反馈的不足,并实现了安全的微创切除和重建。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef15/7826591/0de56872bb5e/jcm-10-00229-g001.jpg

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