Wondmkun Yohannes Tsegyie, Ayele Akeberegn Gorems
Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Patient Prefer Adherence. 2021 Jan 6;15:9-14. doi: 10.2147/PPA.S285064. eCollection 2021.
Because systemic corticosteroids are associated with severe adverse effects, a study on the prescribing pattern for rationalizing drug therapy is needed.
The purpose of this study was to assess the prescription pattern of systemic steroidal drugs at the outpatient department of Menelik II Referral Hospital, Addis Ababa, Ethiopia, 2019.
A cross-sectional study design was used to assess the prescription pattern of systemic steroidal drugs in the outpatient department of Menelik II Referral Hospital. A total of 384 patient charts were included in the study. The sample was selected by using a non-probability quota sampling method. The data was collected from patient charts by using a checklist and analyzed by using SPSS version 20 computer software package. Finally, the data was presented with tables, graphs and charts.
A total of 384 patient medical charts were reviewed during the study period. From which, 61.2% were females and 22.4% were in the age group of 31-40 years. The majority, 63.5%, of systemic corticosteroid use was indicated for respiratory disorders and the most frequently prescribed drug was prednisolone (42.4%). It was also found that intermediate acting corticosteroids (prednisolone and methyl prednisolone) were mostly prescribed during the study period.
In this study, most steroids were indicated for respiratory disorders and prednisolone was found to be the most widely prescribed medication among systemic steroids.
由于全身性皮质类固醇与严重不良反应相关，因此需要开展一项关于合理用药治疗处方模式的研究。
本研究旨在评估2019年埃塞俄比亚亚的斯亚贝巴梅内利克二世转诊医院门诊部全身性甾体药物的处方模式。
采用横断面研究设计评估梅内利克二世转诊医院门诊部全身性甾体药物的处方模式。本研究共纳入384份患者病历。样本采用非概率配额抽样方法选取。通过使用检查表从患者病历中收集数据，并使用SPSS 20版计算机软件包进行分析。最后，用表格、图表展示数据。
在研究期间共审查了384份患者病历。其中，61.2%为女性，22.4%年龄在31至40岁之间。全身性皮质类固醇使用的大多数（63.5%）用于呼吸系统疾病，最常处方的药物是泼尼松龙（42.4%）。研究期间还发现，中效皮质类固醇（泼尼松龙和甲泼尼龙）的处方量最大。
在本研究中，大多数类固醇用于呼吸系统疾病，泼尼松龙被发现是全身性类固醇中处方最广泛的药物。
